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Ch. 14+15 - Principles of Disease and Epidemiology | Microbial Mechanisms of Pathogenicity
Chapter 11, Problem 14.3a

Which of the following statements is false?
a. E. coli never causes disease.
b. E. coli provides vitamin K for its host.
c. E. coli often exists in a mutualistic relationship with humans.
d. A disease-causing strain of E. coli causes bloody diarrhea.

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Step 1: Understand the role of E. coli in the human body. E. coli is a common bacterium found in the intestines of humans and animals. It is known for its mutualistic relationship with humans, where it can provide benefits such as vitamin K production.
Step 2: Analyze statement a. Consider whether E. coli can cause disease. While many strains are harmless, some strains, like E. coli O157:H7, are pathogenic and can cause diseases such as food poisoning.
Step 3: Evaluate statement b. E. coli is known to synthesize vitamin K, which is essential for blood clotting, and this is a well-documented mutualistic benefit.
Step 4: Consider statement c. E. coli often exists in a mutualistic relationship with humans, providing benefits like vitamin K production and aiding in digestion.
Step 5: Examine statement d. Some strains of E. coli, particularly pathogenic ones, can cause severe symptoms such as bloody diarrhea, indicating that this statement is true.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

E. coli and Human Health

Escherichia coli (E. coli) is a bacterium commonly found in the intestines of humans and animals. While most strains are harmless and play a role in digestion, some can cause serious illnesses. Understanding the dual nature of E. coli is crucial for distinguishing between beneficial and pathogenic strains.
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The Human Microbiome

Mutualism in Microbiology

Mutualism is a type of symbiotic relationship where both organisms benefit. In the case of E. coli, it helps synthesize vitamin K, which is essential for blood clotting, while humans provide a nutrient-rich environment for the bacteria. This relationship exemplifies how certain microbes contribute positively to human health.
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Pathogenic Strains of E. coli

Certain strains of E. coli, such as Enterohemorrhagic E. coli (EHEC), are pathogenic and can cause severe gastrointestinal diseases, including bloody diarrhea. These pathogenic strains often possess specific virulence factors that enable them to adhere to intestinal cells and produce toxins, leading to illness.
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Related Practice
Textbook Question

Define symbiosis. Differentiate commensalism, mutualism, and parasitism, and give an example of each.

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Textbook Question

All members of a group of ornithologists studying barn owls in the wild have had

salmonellosis (Salmonella gastroenteritis). One birder is experiencing her third infection. What is the most likely source of their infections?

a. The ornithologists are eating the same food.

b. They are contaminating their hands while handling the owls and nests.

c. One of the workers is a Salmonella carrier.

d. Their drinking water is contaminated.

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Textbook Question

Indicate whether each of the following conditions is typical of subacute, chronic, or acute infections.

a. The patient experiences a rapid onset of malaise; symptoms last 5 days.

b. The patient experiences cough and breathing difficulty for months.

c. The patient has no apparent symptoms and is a known carrier.

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Textbook Question

Among hospital patients who have infections, one-third did not enter the hospital with the infection but rather acquired it in the hospital. How do they acquire these infections? What is the method of transmission of these infections? What is the reservoir of infection?

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Textbook Question

Which of the following is not one of Koch's postulates?

a. The same pathogen must be present in every case of the disease.

b. The pathogen must be isolated and grown in pure culture from the diseased host.

c. The pathogen from pure culture must cause the disease when inoculated into a healthy, susceptible laboratory animal.

d. The disease must be transmitted from a diseased animal to a healthy, susceptible animal by direct contact.

e. The pathogen must be isolated in pure culture from an experimentally infected lab animal.

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Textbook Question

Distinguish symptoms from signs as signals of disease.

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