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Ch. 14+15 - Principles of Disease and Epidemiology | Microbial Mechanisms of Pathogenicity
Chapter 11, Problem 14.3a

Indicate whether each of the following conditions is typical of subacute, chronic, or acute infections.
a. The patient experiences a rapid onset of malaise; symptoms last 5 days.
b. The patient experiences cough and breathing difficulty for months.
c. The patient has no apparent symptoms and is a known carrier.

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1
Understand the definitions of acute, subacute, and chronic infections.
Acute infections are characterized by a rapid onset and short duration.
Chronic infections develop slowly and last for a long time, often months or years.
Subacute infections have a duration and onset that is between acute and chronic.
Analyze each condition based on these definitions to determine the type of infection.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Acute Infections

Acute infections are characterized by a rapid onset of symptoms that typically last for a short duration, often days to a few weeks. These infections can lead to significant illness but are usually self-limiting. An example is the flu, where symptoms appear suddenly and resolve relatively quickly.
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Chronic Infections

Chronic infections persist over a long period, often for months or years, and may have intermittent symptoms or be asymptomatic. These infections can lead to long-term health issues and require ongoing management. Conditions like tuberculosis or chronic hepatitis are examples where patients may experience prolonged symptoms or remain carriers.
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Subacute Infections

Subacute infections fall between acute and chronic infections, featuring a gradual onset of symptoms that last longer than acute infections but are not as prolonged as chronic ones. They may last from weeks to a few months and can sometimes resolve without treatment. An example includes subacute bacterial endocarditis, which develops slowly and can lead to serious complications.
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Related Practice
Textbook Question

Use the following information to answer questions 8–10.


A Maryland woman was hospitalized with dehydration. V. cholerae and Plesiomonas shigelloides were isolated from the patient, who had neither traveled outside the United States nor eaten raw shellfish during the preceding month. The patient had attended a party before hospitalization. Two other people at the party had acute diarrheal illness and elevated levels of serum antibodies against Vibrio. Everyone at the party ate crabs and rice pudding with coconut milk. Crabs left over from this party were served at a second party. One of the people at the second party had onset of mild diarrhea; specimens from of these people were negative for vibriocidal antibodies.


The source of the disease was

a. Plesiomonas shigelloides.

b. crabs.

c. V. cholerae.

d. coconut milk.

e. rice.

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Textbook Question

Define symbiosis. Differentiate commensalism, mutualism, and parasitism, and give an example of each.

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Textbook Question

All members of a group of ornithologists studying barn owls in the wild have had

salmonellosis (Salmonella gastroenteritis). One birder is experiencing her third infection. What is the most likely source of their infections?

a. The ornithologists are eating the same food.

b. They are contaminating their hands while handling the owls and nests.

c. One of the workers is a Salmonella carrier.

d. Their drinking water is contaminated.

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Textbook Question

Which of the following statements is false?

a. E. coli never causes disease.

b. E. coli provides vitamin K for its host.

c. E. coli often exists in a mutualistic relationship with humans.

d. A disease-causing strain of E. coli causes bloody diarrhea.

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Textbook Question

Among hospital patients who have infections, one-third did not enter the hospital with the infection but rather acquired it in the hospital. How do they acquire these infections? What is the method of transmission of these infections? What is the reservoir of infection?

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Textbook Question

Which of the following is not one of Koch's postulates?

a. The same pathogen must be present in every case of the disease.

b. The pathogen must be isolated and grown in pure culture from the diseased host.

c. The pathogen from pure culture must cause the disease when inoculated into a healthy, susceptible laboratory animal.

d. The disease must be transmitted from a diseased animal to a healthy, susceptible animal by direct contact.

e. The pathogen must be isolated in pure culture from an experimentally infected lab animal.

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