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Ch. 14+15 - Principles of Disease and Epidemiology | Microbial Mechanisms of Pathogenicity
Chapter 11, Problem 14.4a

Among hospital patients who have infections, one-third did not enter the hospital with the infection but rather acquired it in the hospital. How do they acquire these infections? What is the method of transmission of these infections? What is the reservoir of infection?

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1
Identify the term 'nosocomial infections' which refers to infections acquired in a hospital setting.
Understand that these infections can be acquired through various methods of transmission such as direct contact with healthcare workers, contaminated surfaces, or medical equipment.
Recognize that the reservoir of infection can include the hospital environment itself, healthcare workers, other patients, or even the patient's own microbiota.
Consider the role of inadequate infection control practices, such as improper hand hygiene or sterilization procedures, in the spread of these infections.
Explore the importance of implementing strict infection control measures to prevent the transmission of nosocomial infections.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Healthcare-Associated Infections (HAIs)

Healthcare-Associated Infections (HAIs) are infections that patients acquire while receiving treatment for medical or surgical conditions. These infections can occur in various healthcare settings, including hospitals, and are often caused by pathogens that are resistant to antibiotics. Understanding HAIs is crucial for implementing effective infection control measures.
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Transmission Routes

Infections can be transmitted through several routes, including direct contact, airborne transmission, and vector-borne transmission. In a hospital setting, direct contact with contaminated surfaces or healthcare workers can facilitate the spread of pathogens. Recognizing these routes helps in developing strategies to prevent the transmission of infections.
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Reservoirs of Infection

A reservoir of infection refers to the natural habitat of a pathogen where it lives, grows, and multiplies. In healthcare settings, reservoirs can include patients, healthcare workers, equipment, and the environment. Identifying reservoirs is essential for controlling the spread of infections and implementing appropriate hygiene practices.
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Related Practice
Textbook Question

All members of a group of ornithologists studying barn owls in the wild have had

salmonellosis (Salmonella gastroenteritis). One birder is experiencing her third infection. What is the most likely source of their infections?

a. The ornithologists are eating the same food.

b. They are contaminating their hands while handling the owls and nests.

c. One of the workers is a Salmonella carrier.

d. Their drinking water is contaminated.

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Textbook Question

Indicate whether each of the following conditions is typical of subacute, chronic, or acute infections.

a. The patient experiences a rapid onset of malaise; symptoms last 5 days.

b. The patient experiences cough and breathing difficulty for months.

c. The patient has no apparent symptoms and is a known carrier.

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Textbook Question

Which of the following statements is false?

a. E. coli never causes disease.

b. E. coli provides vitamin K for its host.

c. E. coli often exists in a mutualistic relationship with humans.

d. A disease-causing strain of E. coli causes bloody diarrhea.

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Textbook Question

Which of the following is not one of Koch's postulates?

a. The same pathogen must be present in every case of the disease.

b. The pathogen must be isolated and grown in pure culture from the diseased host.

c. The pathogen from pure culture must cause the disease when inoculated into a healthy, susceptible laboratory animal.

d. The disease must be transmitted from a diseased animal to a healthy, susceptible animal by direct contact.

e. The pathogen must be isolated in pure culture from an experimentally infected lab animal.

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Textbook Question

Distinguish symptoms from signs as signals of disease.

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Textbook Question

Which one of the following diseases is not correctly matched to its reservoir?

a. influenza-animal

b. rabies-animal

c. botulism-nonliving

d. anthrax-nonliving

e. toxoplasmosis-cats

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