How are mutations in histone acetylation (HAT) genes linked to cancer?

Video transcript

Hello everyone and welcome to today's video. So which of the following is true regarding the Houston as gene as answer choice. A we have normal Histon acetyl genes are linked to neoplasms B. Aran, histon acetyl genes can function as ona genes C both A and B D, none of the above. So in order to solve this problem, we really need to understand something. These histon acetyl genes, if they function normally, then there is usually no issue for the cell but sometimes they can become abnormal due to certain mutations or other issues in the cell. Now, when these histon acetyl genes become abnormal, they're going to be causing these Aran or these increased acetyl in the his within the nucleus. And this is going to be activating certain malignant proteins through this aberrant acetyl of the his and these malignant proteins are going to contribute to cancer development and some cancers that can be caused due to these histon acyl genes are for example, breast or ovarian cancers. Now, because these histon acetyl genes can lead to certain cancers. If they become abnormal, they can be called oncogenes. So the correct answer for this question is going to be answer choice. B Aran Houston A genes can function as AA genes. I really hope this video helped you and I hope to see you on the next one.