Skip to main content
Ch. 14 - Translation and Proteins
Chapter 14, Problem 4

The mRNA formed from the repeating tetranucleotide UUAC incorporates only three amino acids, but the use of UAUC incorporates four amino acids. Why?

Verified step by step guidance
1
insert step 1> Identify the repeating tetranucleotide sequences: UUAC and UAUC.
insert step 2> Understand that mRNA is read in sets of three nucleotides, called codons, during translation.
insert step 3> Determine the possible codons from the sequence UUAC: UUA, UAC, ACU, and CUA.
insert step 4> Determine the possible codons from the sequence UAUC: UAU, AUC, UCA, and CUA.
insert step 5> Compare the number of unique codons formed from each sequence and relate them to the number of amino acids incorporated.

Verified Solution

Video duration:
2m
This video solution was recommended by our tutors as helpful for the problem above.
Was this helpful?

Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Tetranucleotide Structure

A tetranucleotide consists of four nucleotides in a specific sequence. In the context of mRNA, the sequence of nucleotides determines the codons, which are groups of three nucleotides that code for specific amino acids. The arrangement of these nucleotides affects how many unique codons can be formed, influencing the number of amino acids incorporated during protein synthesis.
Recommended video:
Guided course
03:53
Ribosome Structure

Codon Usage

Codons are sequences of three nucleotides in mRNA that correspond to specific amino acids during translation. The genetic code is degenerate, meaning that multiple codons can code for the same amino acid. The difference in the number of amino acids incorporated from the two mRNA sequences (UUAC vs. UAUC) is due to the variation in codon combinations that can be formed from the respective tetranucleotides.
Recommended video:
Guided course
11:43
The Genetic Code

Amino Acid Incorporation

The process of incorporating amino acids into a growing polypeptide chain during translation is dictated by the mRNA sequence. Each unique codon corresponds to a specific amino acid, and the total number of distinct codons determines how many different amino acids can be added. In this case, the tetranucleotide UUAC produces fewer unique codons than UAUC, leading to the incorporation of fewer amino acids.
Recommended video: