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Ch. 13 - The Genetic Code and Transcription
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All textbooksKlug 12th EditionCh. 13 - The Genetic Code and TranscriptionProblem 29

Chapter 13, Problem 29

RNAi is currently being tested as a therapeutic tool for genetic diseases and other conditions. Consider the following: cystic fibrosis caused by loss of function of the CFTR gene, HIV infection, and cancer caused by hyperactivity of a growth factor receptor. Which of these may be treatable by RNAi, and which not? Explain your reasoning.

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Hello, everyone. Here we have a question that says RNA interference shows fascinating promise as a tool in molecular biology for genetic diseases and other conditions like cancer, cystic fibrosis, etcetera. The mode of action of RNA, I is a cutting D N A at a specific site. This is the function of restriction indo nucleus. So A is incorrect be regulating gene expression by gene silencing at the stage of translation or by blocking its translation into protein RNA interference or post transcription of gene silencing is a conserved biological response to double stranded RNA that mediates resistance to both genius parasitic and exogenous pathogenic nucleic acids and regulates the expression of protein coding genes. So B is correct. See, transcribing DNA into RNA. This is done by RNA collaborates enzyme. So C is incorrect. D breaking hydrogen bonds between complementary pairs during DNA replication. This is catalyzed by hell A cases. So D is wrong. So our answer here is B. Thank you for watching. Bye.
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