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Ch. 13 - The Genetic Code and Transcription

Chapter 13, Problem 25

Substitution RNA editing is known to involve either C-to-U or A-to-I conversions. What common chemical event accounts for each?

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Hi everyone. Let's take a look at this practice problem together. Which enzyme catalyze is the conversion of A to I and C. To you in substitution RNA editing. Now recall that substitution RNA editing is where you can have specific nucleotides. Change to provide RNA and protein diversity but it doesn't affect the genomic DNA. So in substitution RNA editing you can have the conversion of adding to in a scene and cytosine to uracil. Now, taking a look at all the answer options. Note that they all begin with D. D. E. What this means is that the enzyme that catalyze is the conversions is going to be removing something. So this could be an atom a molecule, a functional group. It's the removal of something. So let's take a look at the options further. We have a D oxygen ease this is removal of an oxygen for B. We have D hydrogen is which is the removal of hydrogen. Then we have C. D. Car box allays, which is the removal of carbon dioxide or a ceo to group. And then we have D. D. A. Means which is the removal of an amino group or an NH two. So what I want to do is take a look at these conversions. Look at the chemical structures. So on the top we have adenine being converted to in a scene and you'll note that the differences in the molecule occur right where I have highlighted. Now what happens is you get the loss of this group which is an amino group. Now if we take a look at Cytisine to your cell. this is the difference between the two molecules right there and you also get the loss of the amino group. So in each of these conversions, an enzyme which is part of a broader group called amenities, is is what converts add in into in a scene and then sight unseen to yourself. So the correct answer is D. D. A means. And just to reiterate, it's not the same enzyme that does both conversions, but two different enzymes that are both considered D amazes. Alright, everyone. I hope you found this helpful and I'll see you soon for the next practice problem.
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