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Ch. 12 - DNA Organization in Chromosomes

Chapter 12, Problem 9

Describe the molecular composition and arrangement of the components in the nucleosome.

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Hi everyone. Welcome back. Let's look at our next question. It says Which his stone links one core particle to the other in the linker DNA. So when we think about our histone, let's recall, we've got two types of histone proteins. We've got the core his stones, those are H. Two, A. H. Two, B. H. Three and H. Four and four dime ear's core. His stones make up the oct immer that DNA wraps around to form a nuclear zone. Those little beads on the strength. But then we have the linker histone H. One and H. Five. They bind the linker DNA. In the nucleus OEMs that enhances the condensation of the chroma tin that causes that solenoid structure as the crow metin goes around in a helix to pack even more tightly together. So the his stone that links one core particle to the other in linker D. N. A. When we look at our answer choices um Choice A. Is H. Two A. But that's one of the core his stones same with choice b. h. three. But choice C. Here is H. One which is one of our linker his stones and then Choice D. Is H. Four. Also a core histone. So choice ch one is one of the linker histone that links one core particle to the other. Um In the linker D. N. A. You in the next video