4. Genetic Mapping and Linkage
Chi Square and Linkage
Problem 30a
Textbook Question
Textbook QuestionA Drosophila experiment examining potential genetic linkage of X-linked genes studies a recessive eye mutant (echinus), a recessive wing-vein mutation (crossveinless), and a recessive bristle mutation (scute). The wild-type phenotypes are dominant. Trihybrid wild-type females (all have the same genotype) are crossed to hemizygous males displaying the three recessive phenotypes. Among the 20,765 progeny produced from these crosses are the phenotypes and numbers listed in the table. Any phenotype not given is wild type. Phenotype Number 1. Echinus 8576 2. Scute 977 3. Crossveinless 716 4. Echinus, scute 681 5. Scute, crossveinless 8808 6. Scute, crossveinless, echinus 4 7. Echinus, crossveinless 1002 8. Wild type 1 20,765 Use chi-square analysis to demonstrate that the data in this experiment are not the result of independent assortment.
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