15. Genomes and Genomics
Functional Genomics
Problem 19a
Textbook Question
Textbook QuestionA 1.0-kb DNA fragment from the end of the mouse gene described in the previous problem is examined by DNA footprint protection analysis (see Research Technique 8.1). Two samples are end-labeled with ³²P and one of the two is mixed with TFIIB, TFIID, and RNA polymerase II. The DNA exposed to these proteins is run in the right-hand lane of the gel shown below and the control DNA is run in the left-hand. Both DNA samples are treated with DNase I before running the samples on the electrophoresis gel. Explain the role of DNase I.
![](/channels/images/assetPage/verifiedSolution.png)
This video solution was recommended by our tutors as helpful for the problem above
Video duration:
2mPlay a video:
98
views
Was this helpful?
Related Videos
Related Practice