6. Chromosomal Variation
Chromosomal Rearrangements: Deletions
Problem 32f
Textbook Question
Textbook QuestionA healthy couple with a history of three previous spontaneous abortions has just had a child with cri-du-chat syndrome, a disorder caused by a terminal deletion of chromosome 5. Their physician orders karyotype analysis of both parents and of the child. The karyotype results for chromosomes 5 and 12 are shown here. Which parent has an abnormal karyotype? How can you tell? What is the nature of the abnormality?
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