The six nucleotides preceding the start codon and the fi...

Question

The six nucleotides preceding the start codon and the first nucleotide after the start codon in eukaryotes exhibit strong sequence conservation as determined by the percentages of nucleotides in the to positions and the position (see Problem 34). Use the data given in the table for Problem 35 to determine the seven nucleotides that most commonly surround the start in vertebrates.

Accepted Answer

Hello everyone and welcome to today's video. So in a study of the gene in different species, the following sequence was obtained for a conserved region. So species one is a G T C C G AC G T species two is a G T C C G ac G T. Species three is a G T C T G AC G T. Species four is a G T C C G A T G T species five is a G T C C G AC G T and species six is a G T C C G AC G T. So based on the above data, determine the consensus sequence for this conserved region. As answer choice A, we have a G T C T G ac G T as answer choice B, we have a G T C C G ac G T as answer choice C. We have a G C C tt A G G A and as answer choice Z we have a G TT C C G G A T, well as it turns out these conserved regions in order to come up with a consensus sequence for this conserved region. All we have to do is look at each place. And the term the most common nucleotide or nitrogenous base for each. Now, for example, for the number one place in each of the species, the most common nucleotide is going to be a. So that will be the first one for us. Then for the second spot, the most common is going to be g looking at all of the species, all will be the second place. Then the third place, the most common one is going to be for the fourth place. The most common one is going to be C for the fifth place. The most common one is going to be C again. Although we have A T in species three, it is not going to be the most common nucleotide for these spot. Then we have the next one which the most common one is going to be G. Finally, we have A which or just the next one, which the most common one will be a, then the next one, the most common one is going to be C again then and finally, so A G T C C G ac G and T is going to be the consensus sequence, which is the most common sequence that we were able to pull from all of these species. So the correct answer choice for this question is going to be answer choice B which is the same as the consensus sequence that we were able to obtain I really hope this video helped you and I hope to see you on the next one.

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