Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
3. Extensions to Mendelian Inheritance
Sex Chromosome
2:20 minutes
Problem 29a
Textbook Question
Textbook QuestionA wild-type Drosophila male and female are crossed, producing 324 female progeny and 161 male progeny. All their progeny are wild type.
Propose a genetic hypothesis to explain these data.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Sex-linked Inheritance
In Drosophila, certain traits are often linked to sex chromosomes, particularly the X chromosome. Males have one X and one Y chromosome, while females have two X chromosomes. If a trait is sex-linked, it can exhibit different inheritance patterns in males and females, which is crucial for understanding the progeny ratios observed in the cross.
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Sex-Linked Genes
Wild-type Phenotype
The wild-type phenotype refers to the most common or typical form of a trait found in a natural population. In this case, all progeny being wild type suggests that the alleles for the traits being studied are dominant or that the wild-type allele is present in both parents, leading to the expression of the wild-type phenotype in all offspring.
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Mutations and Phenotypes
Progeny Ratio Analysis
Analyzing the ratio of male to female progeny can provide insights into the genetic mechanisms at play. In this scenario, the ratio of 324 females to 161 males suggests a potential sex-linked inheritance pattern, as the expected ratio for a typical Mendelian cross would be 1:1 for male and female offspring, indicating that the trait may be influenced by the sex chromosomes.
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