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Ch. 42 - Gas Exchange and Circulation
Chapter 41, Problem 12

During exercise, the cardiovascular system must supply muscles with large amounts of oxygen and fuel and get rid of a lot of wastes. How do the cardiovascular systems of athletes respond to prolonged exercise? When athletes exercise, what is the primary physiological variable responsible for their sustained increase in ventilation rate? a. decreased blood PO2 b. increased blood PCO2 c. increased blood pH d. increased body temperature

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The cardiovascular system of athletes adapts to prolonged exercise by increasing cardiac output (the amount of blood the heart pumps per minute) and redistributing blood flow to the muscles. This is achieved through an increase in heart rate and stroke volume (the amount of blood pumped per heartbeat).
During exercise, the blood vessels in the muscles dilate, allowing for increased blood flow to these areas. This process is known as vasodilation and is crucial for delivering oxygen and nutrients to working muscles while removing carbon dioxide and other metabolic wastes.
The cardiovascular adaptations also include an increase in the total volume of blood, which enhances the oxygen-carrying capacity of the blood, providing more oxygen to the muscles.
The primary physiological variable responsible for the sustained increase in ventilation rate during exercise in athletes is 'b. increased blood PCO2'. As exercise intensity increases, the muscles produce more carbon dioxide as a byproduct of metabolism, which leads to an increase in blood PCO2 levels.
The increase in blood PCO2 stimulates chemoreceptors in the body to signal the respiratory center in the brain, leading to an increase in the rate and depth of breathing. This process is known as hyperpnea and helps to expel the excess CO2 and maintain blood pH levels.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Cardiovascular System Function

The cardiovascular system is responsible for transporting oxygen, nutrients, and waste products throughout the body. During exercise, it adapts by increasing heart rate and stroke volume to enhance blood flow to active muscles. This ensures that muscles receive adequate oxygen and glucose while efficiently removing carbon dioxide and other metabolic wastes.
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Ventilation Rate and Gas Exchange

Ventilation rate refers to the amount of air inhaled and exhaled per minute, which increases during exercise to meet the heightened oxygen demands of the body. The primary driver for this increase is the concentration of carbon dioxide (PCO2) in the blood, as elevated levels signal the respiratory center to enhance breathing to expel CO2 and maintain acid-base balance.
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Physiological Responses to Exercise

During prolonged exercise, the body undergoes various physiological changes, including increased heart rate, blood flow redistribution, and enhanced ventilation. These adaptations help maintain homeostasis by ensuring that oxygen delivery meets the metabolic demands of working muscles, while also managing the removal of carbon dioxide and other byproducts of metabolism.
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Related Practice
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Predict how Antarctic icefish can transport enough oxygen in their blood to meet their needs even though they lack hemoglobin.

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Why did separate systemic and pulmonary circulations evolve in species that have the high-pressure circulatory system required for rapid movement of blood?

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Textbook Question

During exercise, the cardiovascular system must supply muscles with large amounts of oxygen and fuel and get rid of a lot of wastes. How do the cardiovascular systems of athletes respond to prolonged exercise? During athletic training, the oxygen–hemoglobin dissociation curve a. shifts to the right, unloading more oxygen to tissues. b. shifts to the right, unloading less oxygen to tissues. c. shifts to the left, unloading more oxygen to tissues. d. shifts to the left, unloading less oxygen to tissues.

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Textbook Question

During exercise, the cardiovascular system must supply muscles with large amounts of oxygen and fuel and get rid of a lot of wastes. How do the cardiovascular systems of athletes respond to prolonged exercise? Researchers used echocardiography, a sonogram of the heart, to estimate the mass of the left ventricle in current athletes, non-athletes, and ex-athletes. The data are graphed below (*** means P<0.001, and the P value comparing non-athletes and ex-athletes is >0.05). What conclusion can be drawn from the graph?

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Textbook Question

During exercise, the cardiovascular system must supply muscles with large amounts of oxygen and fuel and get rid of a lot of wastes. How do the cardiovascular systems of athletes respond to prolonged exercise? Explain the advantage of the observed difference between current athletes and non-athletes in the graph shown here.

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Textbook Question

During exercise, the cardiovascular system must supply muscles with large amounts of oxygen and fuel and get rid of a lot of wastes. How do the cardiovascular systems of athletes respond to prolonged exercise? Researchers have also observed that athletes and non-athletes have the same mean resting cardiac output, even though athletes have a far lower resting heart rate. How is this possible?

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