20. Carboxylic Acid Derivatives:NAS
Acid-Catalyzed Ester Hydrolysis
20. Carboxylic Acid Derivatives:NAS
Acid-Catalyzed Ester Hydrolysis - Video Tutorials & Practice Problems
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Get a 10 bullets summary of the topicAre you having deja vu? You should be! We are learning a mechanism that is the exact opposite of Fischer Esterification.That means instead of going from a Carboxylic Acid to an Ester, we are hydrolyzing an Ester to a Carboxylic Acid.
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General Reaction
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General Mechanism
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PRACTICE PROBLEMS AND ACTIVITIES (35)
- Show the mechanism for the acid-catalyzed formation of 23c starting with the product obtained from its hydroly...
- Aspartame, the sweetener used in the commercial products NutraSweet and Equal, is 200 times sweeter than sucro...
- What products are formed from the acid-catalyzed hydrolysis of the following esters? a. b.
- Using the mechanism for the acid-catalyzed hydrolysis of an ester as your guide, write the mechanism—showing a...
- In the mechanism for the acid-catalyzed hydrolysis of an ester, C. what species is HB+ most likely to be in t...
- When a carboxylic acid is dissolved in isotopically labeled water (H2O18) and an acid catalyst is added, the l...
- Show how you would accomplish the following syntheses. (c) hexan-1-ol → 2-hydroxyheptanoic acid
- Suppose we have some optically pure (R)-2-butyl acetate that has been 'labeled' with the heavy O-18 isotope at...
- Propose a mechanism for the acid-catalyzed hydrolysis of phenylalanine ethyl ester.
- The Reformatsky reaction is an addition reaction in which an organozinc reagent is used instead of a Grignard ...
- Propose mechanisms for the following reactions.(c) <IMAGE>
- Propose mechanisms for the following reactions.(d) <IMAGE>
- The mechanism for acidic hydrolysis of a nitrile resembles the basic hydrolysis, except that the nitrile is fi...
- Compare each of the mechanisms listed here with the mechanism for each of the two parts of the acid-catalyzed ...
- What products would you expect to obtain from the following reactions? c. urea+water d. beta-ethylglutaric a...
- Which ester hydrolyzes more rapidly? a. methyl acetate or phenyl acetate?
- Which ester hydrolyzes more rapidly? b. phenyl acetate or benzyl acetate?
- Compare each of the mechanisms listed here with the mechanism for each of the two parts of the acid-catalyzed ...
- For each heterocyclic compound, (ii) show what compounds would result from complete hydrolysis. (a) (b) (c)
- How could you convert N-methylbenzamide to the following compounds? b. benzoic acid
- How could you convert N-methylbenzamide to the following compounds? d. benzyl alcohol
- Which alkyl halides form the carboxylic acids listed here after reaction with sodium cyanide followed by heati...
- Because bromocyclohexane is a secondary alkyl halide, both cyclohexanol and cyclohexene are formed when the al...
- What reagents would you use to convert methyl propanoate to the following compounds? c. N-ethylpropanamide d...
- Describe how the target molecule (butanone) can be synthesized in a high yield from butane. butane ?—> bu...
- Show how the following compounds could be prepared from the given starting materials. You can use any necess...
- Show how the following compounds could be prepared from the given starting materials. You can use any necess...
- Show how the following compounds could be prepared from the given starting materials. You can use any necess...
- How would you make the following compounds from N-benzylbenzamide? b. benzoic acid
- What are the products of the following reactions? d. + H2O —>
- Propose mechanisms for the following reactions. (a) (b)
- Why do the nitro groups change the relative leaving tendencies of the carboxy and 2,4-dinitrophenoxy groups in...
- Write a mechanism for each of the following reactions: a. the uncatalyzed hydrolysis of methyl propionate.
- (c) The Principle of Microscopic Reversibility states that a forward reaction and a reverse reaction taking pl...
- <IMAGE> (Solved Problem 20-1)(b) Finish the solution for Solved Problem 20-1 by providing a mechanism fo...