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Ch. 14+15 - Principles of Disease and Epidemiology | Microbial Mechanisms of Pathogenicity
Chapter 11, Problem 14.8a

Put the following in the correct order to describe the pattern of disease: period of convalescence, prodromal period, period of decline, incubation period, period of illness.

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Identify the initial stage where the pathogen enters the host and begins to multiply, which is the 'incubation period'.
Recognize the stage where early mild symptoms appear, known as the 'prodromal period'.
Determine the stage where the disease is most severe and symptoms are most apparent, referred to as the 'period of illness'.
Identify the stage where symptoms begin to subside, known as the 'period of decline'.
Conclude with the stage where the body recovers and returns to its pre-disease state, called the 'period of convalescence'.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Stages of Infectious Disease

The stages of infectious disease describe the progression of an illness from initial exposure to recovery. These stages include the incubation period, where the pathogen begins to multiply without causing symptoms, followed by the prodromal period, characterized by early, non-specific symptoms. The period of illness follows, marked by the most severe symptoms, and is succeeded by the period of decline, where symptoms begin to subside, leading to the period of convalescence, where recovery occurs.
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Incubation Period

The incubation period is the time between exposure to a pathogen and the onset of symptoms. During this phase, the pathogen replicates within the host, but the host does not yet exhibit any signs of illness. The length of the incubation period can vary significantly depending on the pathogen and the individual's immune response, influencing the timing of disease detection and intervention.
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Convalescence

Convalescence is the final stage of disease progression, where the patient recovers from the illness. During this period, the body repairs itself, and the immune system works to eliminate any remaining pathogens. The duration of convalescence can vary, and while the patient may feel better, they might still be susceptible to complications or secondary infections.
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Related Practice
Textbook Question

Use the following information to answer questions 6–7.

On September 6, a 6-year-old boy experienced fever, chills, and vomiting. On September 7, the child was hospitalized with diarrhea and swollen lymph nodes under both arms. On September 3, he had been scratched and bitten by a cat. The cat was found dead on September 5, and Y. pestis was isolated from the cat. Chloramphenicol was administered to the child from September 7, when Y. pestis was isolated from his blood. On September 17, the child's temperature returned to normal. On September 22, the child was released from the hospital.


Identify the incubation period for this case of bubonic plague.

a. September 3-5

b. September 3-6

c. September 6-7

d. September 6-17

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Textbook Question

Why are some organisms that constitute the normal microbiota described as commensals, whereas others are described as mutualistic?

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Textbook Question

Use the following information to answer questions 6–7.

On September 6, a 6-year-old boy experienced fever, chills, and vomiting. On September 7, the child was hospitalized with diarrhea and swollen lymph nodes under both arms. On September 3, he had been scratched and bitten by a cat. The cat was found dead on September 5, and Y. pestis was isolated from the cat. Chloramphenicol was administered to the child from September 7, when Y. pestis was isolated from his blood. On September 17, the child's temperature returned to normal. On September 22, the child was released from the hospital


Identify the prodromal period for this disease.

a. September 3-5

b. September 3-6

c. September 6-7

d. September 6-17

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Textbook Question

Use the following information to answer questions 8–10.


A Maryland woman was hospitalized with dehydration. V. cholerae and Plesiomonas shigelloides were isolated from the patient, who had neither traveled outside the United States nor eaten raw shellfish during the preceding month. The patient had attended a party before hospitalization. Two other people at the party had acute diarrheal illness and elevated levels of serum antibodies against Vibrio. Everyone at the party ate crabs and rice pudding with coconut milk. Crabs left over from this party were served at a second party. One of the people at the second party had onset of mild diarrhea; specimens from of these people were negative for vibriocidal antibodies.


This is an example of

a. vehicle transmission.

b. airborne transmission.

c. transmission by fomites.

d. direct contact transmission.

e. healthcare-associated transmission.

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Textbook Question

This microbe is acquired by humans as infants and is essential for good health. Acquiring a closely related strain causes severe stomach cramps, bloody diarrhea, and vomiting. What is the microbe?

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Textbook Question

The Opa gene is used to identify this endotoxin-producing bacterium that grows well in the high- CO₂ conditions inside phagocytes.

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