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Ch. 14+15 - Principles of Disease and Epidemiology | Microbial Mechanisms of Pathogenicity
Chapter 11, Problem 14.7a

Why are some organisms that constitute the normal microbiota described as commensals, whereas others are described as mutualistic?

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1
Understand the definitions: Commensalism is a type of symbiotic relationship where one organism benefits while the other is neither helped nor harmed. Mutualism is a relationship where both organisms benefit.
Identify examples of commensal organisms in the human microbiota, such as certain skin bacteria that live on the surface without affecting the host.
Identify examples of mutualistic organisms in the human microbiota, such as gut bacteria that help in digestion and vitamin production while receiving nutrients and a habitat from the host.
Consider the ecological roles: Commensals may occupy niches that prevent pathogenic organisms from colonizing, while mutualists actively contribute to the host's health.
Reflect on the dynamic nature of these relationships, as some organisms can shift from commensal to mutualistic roles depending on environmental conditions and host health.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Normal Microbiota

Normal microbiota refers to the diverse community of microorganisms that reside on and within the human body without causing disease. These organisms play crucial roles in maintaining health, such as aiding digestion, synthesizing vitamins, and protecting against pathogens. The composition of normal microbiota can vary significantly between individuals and is influenced by factors like diet, environment, and genetics.
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Normal Microflora

Commensalism

Commensalism is a type of symbiotic relationship where one organism benefits while the other is neither helped nor harmed. In the context of normal microbiota, commensal organisms may derive nutrients and a habitat from the host without affecting the host's health. An example is certain skin bacteria that feed on dead skin cells but do not impact the host's well-being.
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Symbiotic Relationships

Mutualism

Mutualism is a symbiotic relationship in which both organisms benefit from the interaction. In the case of mutualistic normal microbiota, these microorganisms contribute to the host's health by performing functions that the host cannot do alone, such as fermenting dietary fibers into short-chain fatty acids. This relationship enhances nutrient absorption and supports the immune system, illustrating the interdependence between host and microbiota.
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Related Practice
Textbook Question

Which one of the following diseases is not correctly matched to its reservoir?

a. influenza-animal

b. rabies-animal

c. botulism-nonliving

d. anthrax-nonliving

e. toxoplasmosis-cats

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Textbook Question

How can a local infection become a systemic infection?

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Textbook Question

Use the following information to answer questions 6–7.

On September 6, a 6-year-old boy experienced fever, chills, and vomiting. On September 7, the child was hospitalized with diarrhea and swollen lymph nodes under both arms. On September 3, he had been scratched and bitten by a cat. The cat was found dead on September 5, and Y. pestis was isolated from the cat. Chloramphenicol was administered to the child from September 7, when Y. pestis was isolated from his blood. On September 17, the child's temperature returned to normal. On September 22, the child was released from the hospital.


Identify the incubation period for this case of bubonic plague.

a. September 3-5

b. September 3-6

c. September 6-7

d. September 6-17

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Textbook Question

Use the following information to answer questions 6–7.

On September 6, a 6-year-old boy experienced fever, chills, and vomiting. On September 7, the child was hospitalized with diarrhea and swollen lymph nodes under both arms. On September 3, he had been scratched and bitten by a cat. The cat was found dead on September 5, and Y. pestis was isolated from the cat. Chloramphenicol was administered to the child from September 7, when Y. pestis was isolated from his blood. On September 17, the child's temperature returned to normal. On September 22, the child was released from the hospital


Identify the prodromal period for this disease.

a. September 3-5

b. September 3-6

c. September 6-7

d. September 6-17

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Textbook Question

Put the following in the correct order to describe the pattern of disease: period of convalescence, prodromal period, period of decline, incubation period, period of illness.

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Textbook Question

Use the following information to answer questions 8–10.


A Maryland woman was hospitalized with dehydration. V. cholerae and Plesiomonas shigelloides were isolated from the patient, who had neither traveled outside the United States nor eaten raw shellfish during the preceding month. The patient had attended a party before hospitalization. Two other people at the party had acute diarrheal illness and elevated levels of serum antibodies against Vibrio. Everyone at the party ate crabs and rice pudding with coconut milk. Crabs left over from this party were served at a second party. One of the people at the second party had onset of mild diarrhea; specimens from of these people were negative for vibriocidal antibodies.


This is an example of

a. vehicle transmission.

b. airborne transmission.

c. transmission by fomites.

d. direct contact transmission.

e. healthcare-associated transmission.

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