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Ch. 13 - Viruses, Viroids, and Prions
Chapter 10, Problem 13.6a

The ability of a virus to infect an organism is regulated by
a. the host species.
b. the type of cells.
c. the availability of an attachment site.
d. cell factors necessary for viral replication.
e. all of the above

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1
Identify the factors that influence a virus's ability to infect an organism.
Consider the role of the host species in viral infection, as different viruses can infect different species.
Evaluate the importance of the type of cells, since viruses often have specific cell types they can infect.
Assess the necessity of an attachment site, which is crucial for the virus to bind and enter the host cell.
Examine the requirement for cell factors necessary for viral replication, as viruses rely on the host's cellular machinery to reproduce.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Host Specificity

Host specificity refers to the range of host organisms that a virus can infect. Different viruses have evolved to target specific species or cell types, which is influenced by the virus's ability to recognize and bind to receptors on the host's cells. This concept is crucial for understanding why certain viruses only infect particular organisms.
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Viral Attachment and Entry

Viral attachment and entry involve the mechanisms by which a virus binds to a host cell and penetrates its membrane. This process is facilitated by specific proteins on the virus surface that interact with receptors on the host cell. The availability of these attachment sites is a critical factor in determining whether a virus can successfully infect a cell.
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Cellular Factors for Viral Replication

Cellular factors for viral replication include the host cell's machinery and resources that viruses exploit to replicate and assemble new viral particles. These factors can include enzymes, nucleotides, and cellular structures necessary for the viral life cycle. Understanding these factors is essential for comprehending how viruses hijack host cells to propagate.
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