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Ch. 11 - Innate Immunity
Chapter 10, Problem 11.21a

Which of the following is a chemical defense found in tears? Select all that apply.
a. Water
b. Lysozyme
c. Antimicrobial peptides
d. Neutrophils

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1
Identify the components of tears that have a chemical defense function.
Understand that chemical defenses are substances that can inhibit or destroy pathogens.
Recall that lysozyme is an enzyme found in tears that breaks down bacterial cell walls, thus acting as a chemical defense.
Recognize that antimicrobial peptides are small proteins that can destroy bacteria, fungi, and viruses, and are also present in tears.
Conclude that lysozyme and antimicrobial peptides are the chemical defenses found in tears.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Chemical Defenses in Tears

Tears contain various chemical defenses that help protect the eyes from pathogens. These include enzymes and antimicrobial substances that can inhibit bacterial growth and provide a first line of defense against infections.
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Lysozyme

Lysozyme is an enzyme found in various body fluids, including tears, that breaks down the cell walls of certain bacteria, leading to their destruction. It plays a crucial role in the innate immune response by providing antimicrobial activity.
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Antimicrobial Peptides

Antimicrobial peptides are small proteins that can kill bacteria, fungi, and viruses. They are part of the innate immune system and are present in tears, contributing to the overall antimicrobial properties of the ocular surface.
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Related Practice
Textbook Question

Which of the following shows a correct chronological order of events in inflammation?

a. Neutrophil recruitment, macrophage recruitment, vascular changes, resolution

b. Vascular changes, resolution, neutrophil recruitment, macrophage recruitment

c. Vascular changes, macrophage recruitment, neutrophil recruitment, resolution

d. Vascular changes, macrophage recruitment, resolution, neutrophil recruitment

e. Vascular changes, neutrophil recruitment, macrophage recruitment, resolution

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Textbook Question

Pick which statements are true, then correct all false statements, so they are also true.

a. Redness, pain, fever, and swelling characterize inflammation.

b. Granulocytes include monocytes and lymphocytes.

c. Pyrogens induce fever.

d. Adaptive and innate immune responses are completely independent from one another.

e. The innate immune responses occur faster than adaptive responses.

f. Monocytes are highly phagocytic cells.

g. Complement cascades share the same outcomes: opsonization, cytolysis, and fever.

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Textbook Question

Select all the false statements about fever.

a. It is generated by pyrogens.

b. It is an innate immune defense.

c. It is accompanied by a decrease in metabolism.

d. It can be reduced by anti-inflammatory drugs.

e. It can accompany inflammation.

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Textbook Question

Which of the following are formed elements of the blood? Select all that apply. (NCLEX/HESI/TEAS)

a. Platelet

b. Leukocyte

c. Plasma

d. Erythrocyte

e. Complement proteins

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Textbook Question

Match the following fever terms to their proper definition; not all definitions will be used.

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Textbook Question

Which of the following would most directly reduce fever? Select all that apply. (NCLEX/HESI/TEAS)

a. Limiting the number of circulating white blood cells

b. Reducing eicosanoid production

c. Inhibiting pyrogenic cytokines

d. Stimulating the action of prostaglandins

e. Administering antihistamines

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