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Ch. 9 - Controlling Microbial Growth in the Environment
Chapter 9, Problem 9.16a

Which of the following chemicals is active against bacterial endospores?


a. copper ions
b. ethylene oxide
c. ethanol
d. triclosan

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1
Understand the nature of bacterial endospores: Bacterial endospores are highly resistant structures formed by certain bacteria, such as Bacillus and Clostridium species, to survive extreme conditions.
Identify the properties of each chemical option: Consider the mechanism of action and effectiveness of each chemical against endospores.
Evaluate copper ions: Copper ions are known for their antimicrobial properties but are generally not effective against endospores.
Evaluate ethylene oxide: Ethylene oxide is a gaseous sterilizing agent that can penetrate and destroy endospores, making it effective against them.
Evaluate ethanol and triclosan: Ethanol is a common disinfectant but is not effective against endospores, and triclosan is an antibacterial agent that does not target endospores.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Bacterial Endospores

Bacterial endospores are highly resistant structures formed by certain bacteria, such as Bacillus and Clostridium species, to survive extreme environmental conditions. They are dormant forms that can withstand heat, desiccation, and chemical disinfectants, making them a significant challenge in microbiology and sterilization processes.
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Chemical Disinfectants

Chemical disinfectants are substances used to eliminate or reduce harmful microorganisms on surfaces and in materials. Different disinfectants have varying mechanisms of action and effectiveness against specific types of microbes, including bacteria, viruses, and fungi. Understanding the spectrum of activity of these chemicals is crucial for effective infection control.
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Sterilization Methods

Sterilization methods are techniques used to destroy all forms of microbial life, including endospores. Common methods include heat (autoclaving), radiation, and chemical agents like ethylene oxide. Each method has its own advantages and limitations, and the choice of method depends on the type of material being sterilized and the level of microbial resistance.
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