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Ch.26 Nucleic Acids and Protein Synthesis
Chapter 26, Problem 26.57

Which amino acid(s) have the most codons?

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1
Identify the genetic code table, which shows the codons for each amino acid.
Count the number of codons associated with each amino acid in the genetic code table.
Compare the counts to determine which amino acid(s) have the highest number of codons.
Note that some amino acids have more codons due to the redundancy of the genetic code, which is known as 'degeneracy'.
Conclude by identifying the amino acid(s) with the most codons based on your comparison.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Codons

Codons are sequences of three nucleotides in mRNA that correspond to specific amino acids or stop signals during protein synthesis. There are 64 possible codons, but only 20 standard amino acids, leading to redundancy in the genetic code. This means that multiple codons can code for the same amino acid, which is crucial for understanding which amino acids have the most codons.
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Amino Acids

Amino acids are organic compounds that serve as the building blocks of proteins. There are 20 standard amino acids, each defined by its unique side chain or R group. Some amino acids, like leucine and serine, are encoded by multiple codons, making them more versatile in terms of genetic coding and important for understanding the distribution of codons among amino acids.
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Genetic Code Redundancy

Genetic code redundancy refers to the phenomenon where multiple codons can specify the same amino acid. This redundancy provides a buffer against mutations, as changes in the DNA sequence may not always lead to changes in the protein produced. Understanding this concept is essential for identifying which amino acids have the most codons, as it highlights the relationship between codon usage and amino acid frequency.
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