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Ch. 26 - Population and Evolutionary Genetics

Chapter 25, Problem 18

What are considered significant factors in maintaining the surprisingly high levels of genetic variation in natural populations?

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Hi, everybody. Let's look at our next problem. All of the following are factors that contribute to maintaining high levels of genetic variation in natural populations. Except so let's recall that we're going to look for the answer that does not contribute to maintaining those high levels of genetic variation in natural populations. When we look over our answer choices, we see they are a mutation. B gene flow, see genetic drift and D gene therapy. Well, here's where we want to zoom in on that phrase, natural populations because we can pick out right away that our answer choice would be choice. D gene therapy as that's not going to be part of genetic variation in a natural population. This is obviously something human mediated in which humans alter the genome of an attempt to prevent disease or mitigate the effects of a disease. So, gene therapy right away is going to be our answer. But let's just go through other answer. Choices to be thorough choice. A mutation obviously changes to D N A whether arising spontaneously or through some sort of external force like UV radiation. And this is probably this is the means by which we have genetic variation because the DNA changes and those changes get affected by the natural environment, they might be selected for or against in a population as they might give greater or lesser fitness to the organisms that carry those mutations. So it definitely is a factor that contributes to maintaining genetic variation. So not our answer choice and gene flow is the movement of genes from one population to another. This can happen through migration from one place to another or hybridization, interbreeding of two different species or two different varieties. And this obviously does contribute to genetic variation. It can introduce new alleles into a population. So not our answer choice. And then finally, genetic drift, which is the random fluctuation of allele frequencies due to chance, not natural selection, but something like a group population that moves from one area to another just happens to have a higher representation of certain that's rather rare in the larger population or we have um higher numbers of a certain survive or are killed in some sort of plague or natural disaster. So, fluctuations and a low frequencies due to chance and this does maintain high levels of genetic variations in large populations. We often think of it in small populations where it can cause a loss of genetic variation. So if you have a smaller group that breaks off and it has a smaller representation of certain alley that you can lose genetic variation, but in large populations, it can contribute to genetic diversity since it might result in the prevalence of multiple alleles that might otherwise get selected against by natural selection. Perhaps just by chance, certain alleles continue to coexist in the population. So since that can contribute to levels of genetic variation, that's also another answer. So again, all of the following are factors that contribute to maintaining high levels of genetic variation and natural populations except choice D gene therapy. In the next video.
Related Practice
Textbook Question

Describe how populations with substantial genetic differences can form. What is the role of natural selection?

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Textbook Question

Achondroplasia is a dominant trait that causes a characteristic form of dwarfism. In a survey of 50,000 births, five infants with achondroplasia were identified. Three of the affected infants had affected parents, while two had normal parents. Calculate the mutation rate for achondroplasia and express the rate as the number of mutant genes per given number of gametes.

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Textbook Question

A recent study examining the mutation rates of 5669 mammalian genes (17,208 sequences) indicates that, contrary to popular belief, mutation rates among lineages with vastly different generation lengths and physiological attributes are remarkably constant [Kumar, S., and Subramanian, S. (2002). Proc. Natl. Acad. Sci. USA 99:803–808]. The average rate is estimated at 12.2×10⁻⁹ per bp per year. What is the significance of this finding in terms of mammalian evolution?

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Textbook Question

A botanist studying water lilies in an isolated pond observed three leaf shapes in the population: round, arrowhead, and scalloped. Marker analysis of DNA from 125 individuals showed the round-leaf plants to be homozygous for allele r1, while the plants with arrowhead leaves were homozygous for a different allele at the same locus, r2. Plants with scalloped leaves showed DNA profiles with both the r1 and r2 alleles. Frequency of the r1 allele was estimated at 0.81. If the botanist counted 20 plants with scalloped leaves in the pond, what is the inbreeding coefficient F for this population?

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Textbook Question

A farmer plants transgenic Bt corn that is genetically modified to produce its own insecticide. Of the corn borer larvae feeding on these Bt crop plants, only 10 percent survive unless they have at least one copy of the dominant resistance allele B that confers resistance to the Bt insecticide. When the farmer first plants Bt corn, the frequency of the B resistance allele in the corn borer population is 0.02. What will be the frequency of the resistance allele after one generation of corn borers have fed on Bt corn?

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Textbook Question

In an isolated population of 50 desert bighorn sheep, a mutant recessive allele c when homozygous causes curled coats in both males and females. The normal dominant allele C produces straight coats. A biologist studying these sheep counts four with curled coats. She also takes blood samples from the population for DNA analysis, which reveals that 17 of the sheep are heterozygous carriers of the c allele. What is the inbreeding coefficient F for this population?

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