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Ch. 26 - Population and Evolutionary Genetics

Chapter 25, Problem 20

A farmer plants transgenic Bt corn that is genetically modified to produce its own insecticide. Of the corn borer larvae feeding on these Bt crop plants, only 10 percent survive unless they have at least one copy of the dominant resistance allele B that confers resistance to the Bt insecticide. When the farmer first plants Bt corn, the frequency of the B resistance allele in the corn borer population is 0.02. What will be the frequency of the resistance allele after one generation of corn borers have fed on Bt corn?

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Hi, everybody. Let's take a look at this practice problem together given that the initial frequency of the capital B resistance A lil in the corn borer population is 0.3. What would be the frequency of the recessive genotype? Little B, little B? So in the corn borer population, the question tells us that the recess of A lil is little B. Therefore capital B is the dominant a little. So how do we use the frequency of the dominant A will to solve for the frequency of the recessive genotype? Recall that we will use the Hardy Weinberg equation on the screen. Let's review it. We've got P squared plus two PQ plus Q squared equals one where P is the frequency of the dominant A lil and Q is the frequency of the recessive a little. And also note that P plus Q equals one or the frequency of both alleles has to equal 100%. And then in the equation, we have P squared, P squared represents the frequency of the homocide dominant genotype. So for our question, that is capital B, capital B, Then we have two PQ And two PQ represents the frequency of the Hetero Ziggy's genotype. So for us that is capital B little B, that means Q squared represents the frequency of the Homo zegas recessive genotype, Little B Little B. Okay. Thus far, we've reviewed the Hardy Weinberg Equation. But how do we use it? Recall that in the question, we were told that the frequency of the dominant lil is 0.3, that means we know that p equals 0.3. So there's really just two steps at this point that we're going to use to solve our answer. The first step is we're going to determine que the frequency of the recessive A little using P plus Q equals one. Then we will solve for Q square, the frequency of the Homo Zegas recessive genotype. So let's solve step one, we have P plus Q equals one, 0.3 plus Q equals one. Therefore Q equals 0.7. So this is the frequency of the recessive A little little B. Then we've got step two and step two is Q squared equals 0.7 squared equals 0.49. And this is the frequency of the homesickness recessive genotype. Little B little B. So 0.49 is the correct answer, which means d option D is our correct answer. Alright, everyone. I hope you found this helpful and I'll see you soon for the next practice problem.
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A recent study examining the mutation rates of 5669 mammalian genes (17,208 sequences) indicates that, contrary to popular belief, mutation rates among lineages with vastly different generation lengths and physiological attributes are remarkably constant [Kumar, S., and Subramanian, S. (2002). Proc. Natl. Acad. Sci. USA 99:803–808]. The average rate is estimated at 12.2×10⁻⁹ per bp per year. What is the significance of this finding in terms of mammalian evolution?

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What are considered significant factors in maintaining the surprisingly high levels of genetic variation in natural populations?

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A botanist studying water lilies in an isolated pond observed three leaf shapes in the population: round, arrowhead, and scalloped. Marker analysis of DNA from 125 individuals showed the round-leaf plants to be homozygous for allele r1, while the plants with arrowhead leaves were homozygous for a different allele at the same locus, r2. Plants with scalloped leaves showed DNA profiles with both the r1 and r2 alleles. Frequency of the r1 allele was estimated at 0.81. If the botanist counted 20 plants with scalloped leaves in the pond, what is the inbreeding coefficient F for this population?

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In an isolated population of 50 desert bighorn sheep, a mutant recessive allele c when homozygous causes curled coats in both males and females. The normal dominant allele C produces straight coats. A biologist studying these sheep counts four with curled coats. She also takes blood samples from the population for DNA analysis, which reveals that 17 of the sheep are heterozygous carriers of the c allele. What is the inbreeding coefficient F for this population?

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To increase genetic diversity in the bighorn sheep population described in Problem 23, ten sheep are introduced from a population where the c allele is absent. Assuming that random mating occurs between the original and the introduced sheep, and that the c allele is selectively neutral, what will be the frequency of c in the next generation?

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What genetic changes take place during speciation?

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