Chapter 25, Problem 11
If the initial allele frequencies are p = 0.5 and q = 0.5 and allele a is a lethal recessive, what will be the frequencies after 1, 5, 10, 25, 100, and 1000 generations?
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Consider a population in which the frequency of allele A is p=0.7 and the frequency of allele a is q=0.3 and where the alleles are codominant. What will be the allele frequencies after one generation if the following occurs?
wAA=1, wAa=0.95, waa=0.9
Consider a population in which the frequency of allele A is p=0.7 and the frequency of allele a is q=0.3 and where the alleles are codominant. What will be the allele frequencies after one generation if the following occurs?
wAA=1, wAa=0.99, waa=0.98
Consider a population in which the frequency of allele A is p=0.7 and the frequency of allele a is q=0.3 and where the alleles are codominant. What will be the allele frequencies after one generation if the following occurs?
wAA=0.8, wAa=1, waa=0.8
Under what circumstances might a lethal dominant allele persist in a population?
Assume that a recessive autosomal disorder occurs in 1 of 10,000 individuals (0.0001) in the general population and that in this population about 2 percent (0.02) of the individuals are carriers for the disorder. Estimate the probability of this disorder occurring in the offspring of a marriage between first cousins. Compare this probability to the population at large.
One of the first Mendelian traits identified in humans was a dominant condition known as brachydactyly. This gene causes an abnormal shortening of the fingers or toes (or both). At the time, some researchers thought that the dominant trait would spread until 75 percent of the population would be affected (because the phenotypic ratio of dominant to recessive is 3 : 1). Show that the reasoning was incorrect.