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Ch. 26 - Population and Evolutionary Genetics

Chapter 25, Problem 11

If the initial allele frequencies are p = 0.5 and q = 0.5 and allele a is a lethal recessive, what will be the frequencies after 1, 5, 10, 25, 100, and 1000 generations?

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Everyone, let's take a look at this question together, assuming that a population is in hardy Weinberg equilibrium. What is the value of P. If a recessive trait has a frequency of 5 to 1300 in the population. So let's recall what we know about hardy Weinberg equilibrium. To figure out what the value of P is, if we have that recessive trade frequency of 5 to 1300 so we know that the hardy Weinberg equilibrium formula looks like this where we have P squared plus two PQ plus Q squared equals one. Where P squared is the homesickness dominant? This PQ is the hetero ziggy's frequency and Q squared is the home recessive frequency of the population. And we also know that P plus Q equals one. And since we're trying to find the value of P that means that we have P equals one minus Q. And so looking at the recessive trait frequency, we know that Q squared equals 5 to 1300. Or in other terms five divided by 1300 which means that Q squared equals 0.34. And because we have the square we have to take the square root of both sides and we end up with Q equals 0.62. And because we're trying to find the value of P and we have Q. We plug in Q into this equation and we end up with P equals one minus 0.62 or P equals 0.938, which is answer choice A the correct answer because when this population is in hardy Weinberg equilibrium and we have that Q squared value of 5 to 1300 we do the math and we end up with q squared equals 0.34 and take the square root, so Q 0.62. And that gives us a p value of 0.938. Or answer choice A. The correct answer. I hope you found this video to be helpful. Thank you and goodbye.
Related Practice
Textbook Question

Consider a population in which the frequency of allele A is p=0.7 and the frequency of allele a is q=0.3 and where the alleles are codominant. What will be the allele frequencies after one generation if the following occurs?

wAA=1, wAa=0.95, waa=0.9

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Textbook Question

Consider a population in which the frequency of allele A is p=0.7 and the frequency of allele a is q=0.3 and where the alleles are codominant. What will be the allele frequencies after one generation if the following occurs?

wAA=1, wAa=0.99, waa=0.98

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Textbook Question

Consider a population in which the frequency of allele A is p=0.7 and the frequency of allele a is q=0.3 and where the alleles are codominant. What will be the allele frequencies after one generation if the following occurs?

wAA=0.8, wAa=1, waa=0.8

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Textbook Question

Under what circumstances might a lethal dominant allele persist in a population?

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Textbook Question

Assume that a recessive autosomal disorder occurs in 1 of 10,000 individuals (0.0001) in the general population and that in this population about 2 percent (0.02) of the individuals are carriers for the disorder. Estimate the probability of this disorder occurring in the offspring of a marriage between first cousins. Compare this probability to the population at large.

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Textbook Question

One of the first Mendelian traits identified in humans was a dominant condition known as brachydactyly. This gene causes an abnormal shortening of the fingers or toes (or both). At the time, some researchers thought that the dominant trait would spread until 75 percent of the population would be affected (because the phenotypic ratio of dominant to recessive is 3 : 1). Show that the reasoning was incorrect.

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