Chapter 24, Problem 21
A 3-inch plant was crossed with a 15-inch plant, and all F₁ plants were 9 inches. The F₂ plants exhibited a 'normal distribution,' with heights of 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, and 15 inches.
What will be the outcome if the F₁ plants are testcrossed with plants that are homozygous for all nonadditive alleles?
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Many traits of economic or medical significance are determined by quantitative trait loci (QTLs) in which many genes, usually scattered throughout the genome, contribute to expression.
What general procedures are used to identify such loci?
Many traits of economic or medical significance are determined by quantitative trait loci (QTLs) in which many genes, usually scattered throughout the genome, contribute to expression.
What is meant by the term cosegregate in the context of QTL mapping? Why are markers such as RFLPs, SNPs, and microsatellites often used in QTL mapping?
A 3-inch plant was crossed with a 15-inch plant, and all F₁ plants were 9 inches. The F₂ plants exhibited a 'normal distribution,' with heights of 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, and 15 inches.
What ratio will constitute the 'normal distribution' in the F₂?
In a cross between a strain of large guinea pigs and a strain of small guinea pigs, the F₁ are phenotypically uniform, with an average size about intermediate between that of the two parental strains. Among 1014 F₂ individuals, 3 are about the same size as the small parental strain and 5 are about the same size as the large parental strain. How many gene pairs are involved in the inheritance of size in these strains of guinea pigs?
Type A1B brachydactyly (short middle phalanges) is a genetically determined trait that maps to the short arm of chromosome 5 in humans. If you classify individuals as either having or not having brachydactyly, the trait appears to follow a single-locus, incompletely dominant pattern of inheritance. However, if one examines the fingers and toes of affected individuals, one sees a range of expression from extremely short to only slightly short. What might cause such variation in the expression of brachydactyly?
In a series of crosses between two true-breeding strains of peaches, the F₁ generation was uniform, producing 30-g peaches. The F₂ fruit mass ranges from 38 to 22 g at intervals of 2 g. Using these data, determine the number of polygenic loci involved in the inheritance of peach mass.