Many traits of economic or medical significance are determined by quantitative trait loci (QTLs) in which many genes, usually scattered throughout the genome, contribute to expression.

What is meant by the term cosegregate in the context of QTL mapping? Why are markers such as RFLPs, SNPs, and microsatellites often used in QTL mapping?

Video transcript

Hey everyone, let's take a look at this question together. When the marker locus and the quantitative trait locus consistently co segregate, it means that what, so let's recall what we know about consistent co segregation in relation to the marker locus and the quantitative trait locus. So the word co segregate in relation to the marker locus and the quantitative trait locus or the Q. T. L. Means when two traits are close in proximity they are likely to be inherited together. And this is important for the marker locus as well as the Q. Tl. Because when that marker and the Q. Tl are linked, the various genotype at that marker locus will also vary in their phenotype IQ expression and when they are linked they co segregate. And when you have that consistent co segregation, it implies that the Q. Tl is at or near the D. N. A marker along the chromosome, which means that the correct answer is answer choice C. Because when we have that Q. Tl near that DNA marker, we have consistent co segregation because they are in close proximity and that means that they are linked and are likely to be inherited together. So answer choice C. Is the correct answer. I hope you found this video to be helpful. Thank you and goodbye