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Ch. 23 - Developmental Genetics

Chapter 22, Problem 11

You observe that a particular gene is being transcribed during development. How can you tell whether the expression of this gene is under transcriptional or translational control?

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Hey, everyone. Let's take a look at this question together. These genes are responsible for binding to specific DNA sequences and regulating gene expression. So let's take a look at the following genes to figure out which one of these genes are responsible for binding to specific DNA sequences and regulating gene expression. So, of the following genes, which one is responsible for binding to specific DNA sequences and regulating gene expression, which we know refers to answer choice d transcription factor genes. Because these are the genes that play a crucial role in controlling the transcription of other genes by binding two specific D N A sequences and recruiting the transcription machinery to the gene promoter region. And we know it is not A B or C because master regulatory genes refer to genes that are involved in the development and differentiation of cells and tissues. Signal transducer action genes are the genes that are involved in the transmission signals between cells and answer choice C our genes that are involved in the modifying of the structure of chromatic. And so the only answer choice here that represents those genes that are responsible for Bonnie to specific DNA sequences and regulating gene expression is answer choice D transcription factor genes. I hope you found this video to be helpful. Thank you and goodbye.
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Experiments have shown that any nuclei placed in the polar cytoplasm at the posterior pole of the Drosophila egg will differentiate into germ cells. If polar cytoplasm is transplanted into the anterior end of the egg just after fertilization, what will happen to nuclei that migrate into this cytoplasm at the anterior pole?
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The Drosophila homeotic mutation spineless aristapedia (ssᵃ) results in the formation of a miniature tarsal structure (normally part of the leg) on the end of the antenna. What insight is provided by (ssᵃ) concerning the role of genes during determination?

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Embryogenesis and oncogenesis (generation of cancer) share a number of features including cell proliferation, apoptosis, cell migration and invasion, formation of new blood vessels, and differential gene activity. Embryonic cells are relatively undifferentiated, and cancer cells appear to be undifferentiated or dedifferentiated. Homeotic gene expression directs early development, and mutant expression leads to loss of the differentiated state or an alternative cell identity. M. T. Lewis [(2000). Breast Can. Res. 2:158–169] suggested that breast cancer may be caused by the altered expression of homeotic genes. When he examined 11 such genes in cancers, 8 were underexpressed while 3 were overexpressed compared with controls. Given what you know about homeotic genes, could they be involved in oncogenesis?

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