Embryogenesis and oncogenesis (generation of cancer) share a number of features including cell proliferation, apoptosis, cell migration and invasion, formation of new blood vessels, and differential gene activity. Embryonic cells are relatively undifferentiated, and cancer cells appear to be undifferentiated or dedifferentiated. Homeotic gene expression directs early development, and mutant expression leads to loss of the differentiated state or an alternative cell identity. M. T. Lewis [(2000). Breast Can. Res. 2:158–169] suggested that breast cancer may be caused by the altered expression of homeotic genes. When he examined 11 such genes in cancers, 8 were underexpressed while 3 were overexpressed compared with controls. Given what you know about homeotic genes, could they be involved in oncogenesis?

Video transcript

Hey, everyone. Let's take a look at this question together, which of the following activities do both embryo genesis and Anka genesis share. So let's recall what we know about both embryo genesis and angiogenesis to figure out which of the following activities they both share. So let's talk about what activities we know are found within embryo genesis as well as activities found within Anka genesis. So we know that they're both involved in cell proliferation, which is the increase in the number of cells which during embryo genesis, the cells divide and differentiate to form the various tissues and organs of the developing organism. Whereas an ankle genesis, the cells divide uncontrollably and form tumors. And we also note that both embryo genesis and angiogenesis are involved in the process of a opt Asus which is programmed cell death. And during embryo, gen apoptosis plays a critical role in sculpting the developing tissue and organs by eliminating unnecessary or damaged cells. Whereas an ankle genesis, it is often suppressed, allowing the abnormal cells to survive and accumulate. And lastly, we know that they are both involved in NGO genesis, which is the formation of new blood vessels and during embryo genesis, it is important for the development and growth of organs and tissues. Whereas the genesis is critical for the growth and spread of tumors as new blood vessels supply the tumor with oxygen and nutrients. Therefore, answer choice. D all the above is the correct answer because we know that both embryo genesis and aka genesis share cell proliferation, apoptosis and angiogenesis. So therefore, answer choice. D all the above is the correct answer. I hope you found this video to be helpful. Thank you and goodbye.