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Ch. 15 - Gene Mutation, DNA Repair, and Transposition

Chapter 15, Problem 22

It is estimated that about 0.2 percent of human mutations are due to TE insertions, and a much higher degree of mutational damage is known to occur in some other organisms. In what way might a TE insertion contribute positively to evolution?

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Hello, everyone and welcome to today's video. So which of the following transposes elements moves from one location to another without going through an RN a intermediate stage. Let's look at answer choices B and C first. And the reason why is that these are both retro transposon. Remember that retro transports are going to be using an RNA intermediate to jump from one location to another. These are usually found in retro viruses. Remember that retroviruses use reverse transcript transcript tests to go from RN A to DNA. So this is why these transposon are located within these retroviruses. So for our answer choices, the only transposon that is going to not use RN A and instead is going to use a DNA intermediate to jump from one location to another is going to be answer choice A DNA transposon. So that is the final answer to our question. I really hope this video helped you and I hope to see you on the next one.
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The human genome contains approximately 10⁶ copies of an Alu sequence, one of the best-studied classes of short interspersed elements (SINEs), per haploid genome. Individual Alu units share a 282-nucleotide consensus sequence followed by a 3'-adenine-rich tail region [Schmid (1998)]. Given that there are approximately 3 x 10⁹ base pairs per human haploid genome, about how many base pairs are spaced between each Alu sequence?
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