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Ch. 14 - Translation and Proteins

Chapter 14, Problem 1

In this chapter, we focused on the genetic code and the transcription of genetic information stored in DNA into complementary RNA molecules. Along the way, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions: What experimental evidence provided the initial insights into the compositions of codons encoding specific amino acids?

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Hi everyone Welcome back. Let's look at our next problem. It says the five prime 23 prime direction is the only way to read genetic information. This is referred to as the blank of the genetic code. When we think about directionality something being not the same um from front to back or when rotated, so not symmetrical. Um The word we use in biology is polarity and that indeed is choice. See over here polarity implying that there's a directionality. It matters which way you do or look at something. But let's look at our other choice is to understand why they're not correct choice. Ace has specificity of the word specific and specificity of the genetic code for the fact that a single code on cannot code For more than one amino acid. So the code ons are specific. You can see where to be a problem. If the same code on might refer to this amino acid versus that one. So each code on only code for one amino acid. That's a little confusing because we also have the property down here that we see in choice D of d generous E which says that multiple code owns ken code for the same amino acid. So that's a little confusing to keep that those two things straight. But you can see where that isn't a problem. You know, if this code on code for an amino acid in a slightly different code on codes for the same thing, that doesn't matter. You just don't want to mix up. If you intend a specific will intend a specific amino acid to be in a specific place in a protein that has to be accurate. That has to be specific. But that's why the generous E. Isn't our correct choice either. And finally, Choice B. Universality refers to the fact that all living things on the earth use the same genetic code for their genetic information. So it is universal, but that's not our answer choice. So we're going to cross that out. And again, the five prime three prime direction being the only way to read genetic information. This is referred to as the choice C. Polarity of the genetic code. See you in the next video.
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Textbook Question

In this chapter, we focused on the translation of mRNA into proteins as well as on protein structure and function. Along the way, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations in the chapter, what answers would you propose to the following fundamental questions:

What experimentally derived information led to Holley's proposal of the two-dimensional cloverleaf model of tRNA?

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Textbook Question
In this chapter, we focused on the translation of mRNA into proteins as well as on protein structure and function. Along the way, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations in the chapter, what answers would you propose to the following fundamental questions: How do we know that the structure of a protein is intimately related to the function of that protein?
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Textbook Question
In this chapter, we focused on the genetic code and the transcription of genetic information stored in DNA into complementary RNA molecules. Along the way, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions: Why did geneticists believe, even before direct experimental evidence was obtained, that the genetic code would turn out to be composed of triplet sequences and be nonoverlapping? Experimentally, how were these suppositions shown to be correct?
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Textbook Question
In this chapter, we focused on the genetic code and the transcription of genetic information stored in DNA into complementary RNA molecules. Along the way, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions: How were the specific sequences of triplet codes determined experimentally?
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Textbook Question
In this chapter, we focused on the genetic code and the transcription of genetic information stored in DNA into complementary RNA molecules. Along the way, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions: How were the experimentally derived triplet codon assignments verified in studies using bacteriophage MS2?
268
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Textbook Question
In this chapter, we focused on the translation of mRNA into proteins as well as on protein structure and function. Along the way, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations in the chapter, what answers would you propose to the following fundamental questions: How do we know, based on studies of Neurospora nutritional mutations, that one gene specifies one enzyme?
194
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