Why is Tₘ related to base composition?

Video transcript

Hi everyone. Let's take a look at this practice problem together, identify which of the following 10 base pairs long D. N. A. Sequences will have the highest melting temperature. Here are the D. N. A. Sequences. Recall that the number of hydrogen bonds or the number higher the number of hydrogen bonds, the higher the temperature would need to be in order to melt the D. N. A. Sequences. So the more hydrogen bonds equals a higher melting point. And recall that abdomen and thigh mean form two hydrogen bonds. Whereas guanine and cytosine formed three hydrogen bonds. Since guanine and cytosine have more hydrogen bonds, this means that whatever sequence has the most guanine cytosine base pairs will have the highest melting temperature. So let's count them in A. We have 12 and B. There are zero cytosine guanine base pairs in C. We have 12345678. And Indy we have one too. So our answer is going to be C. Since it has the highest cytosine, guanine base pairs and due to them having the most hydrogen bonds, they'll have the highest melting temperature point. Alright, everyone. I hope you found this helpful and I'll see you soon for the next practice problem