What did the Watson–Crick model suggest about the replication of DNA?

Verified step by step guidance

1. Understand that the Watson-Crick model of DNA describes the structure of DNA as a double helix, with two strands running in opposite directions.
2. Recognize that each strand of the DNA double helix is composed of a sugar-phosphate backbone and nitrogenous bases (adenine, thymine, cytosine, and guanine) that pair specifically (A with T, and C with G) through hydrogen bonds.
3. Consider that the specific base pairing suggests a mechanism for replication: each strand can serve as a template for the formation of a new complementary strand.
4. Visualize that during replication, the two strands of the DNA helix separate, and new nucleotides are added to each template strand according to the base-pairing rules, forming two identical DNA molecules.
5. Reflect on the implication that this semi-conservative replication process ensures that each daughter cell receives an exact copy of the DNA, maintaining genetic continuity across generations.

Key Concepts

Watson-Crick Model

The Watson-Crick model, proposed by James Watson and Francis Crick in 1953, describes the double helix structure of DNA. It illustrates how two strands of DNA are held together by complementary base pairing between adenine-thymine and guanine-cytosine. This model is fundamental for understanding how genetic information is stored and transmitted.

Semi-conservative Replication

The semi-conservative replication mechanism, as suggested by the Watson-Crick model, indicates that during DNA replication, each new DNA molecule consists of one original strand and one newly synthesized strand. This process ensures that genetic information is accurately passed on to daughter cells, maintaining the integrity of the genetic code across generations.

Base Pairing

Base pairing refers to the specific hydrogen bonding between nucleotide bases in DNA, where adenine pairs with thymine and guanine pairs with cytosine. This complementary pairing is crucial for the accurate replication of DNA, as it ensures that each new strand is an exact copy of the original, facilitating the faithful transmission of genetic information.