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Ch.14 - Chemical Kinetics
Chapter 14, Problem 86c

The enzyme urease catalyzes the reaction of urea, 1NH2CONH22, with water to produce carbon dioxide and ammonia. In water, without the enzyme, the reaction proceeds with a first-order rate constant of 4.15 * 10-5 s-1 at 100 C. In the presence of the enzyme in water, the reaction proceeds with a rate constant of 3.4 * 104 s-1 at 21 C. (c) In actuality, what would you expect for the rate of the catalyzed reaction at 100 C as compared to that at 21 C?

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Enzyme Catalysis

Enzyme catalysis refers to the process by which enzymes accelerate chemical reactions by lowering the activation energy required for the reaction to occur. This allows reactions to proceed at a much faster rate compared to uncatalyzed reactions. Enzymes are highly specific and can significantly increase the rate of reactions under physiological conditions, making them essential for biological processes.
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Catalyzed vs. Uncatalyzed Reactions

Rate Constants and Temperature

Rate constants are numerical values that indicate the speed of a reaction at a given temperature. According to the Arrhenius equation, the rate constant increases with temperature due to the increased kinetic energy of molecules, which leads to more frequent and effective collisions. Understanding how temperature affects rate constants is crucial for predicting reaction rates under different conditions.
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First-Order Reactions

First-order reactions are those where the rate of reaction is directly proportional to the concentration of one reactant. This means that if the concentration of the reactant doubles, the reaction rate also doubles. The rate constant for first-order reactions is independent of the concentration of the reactant, making it a key concept in understanding how reaction rates change with the presence of catalysts and varying conditions.
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