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Ch. 46 - Chemical Signals in Animals
Chapter 45, Problem 7

Compare and contrast the structure and function of the anterior and posterior pituitary glands.

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Identify the location and structure of each gland: The anterior pituitary, also known as the adenohypophysis, is located at the front part of the pituitary gland and is glandular in nature. The posterior pituitary, also known as the neurohypophysis, is located at the back part of the pituitary gland and is an extension of the hypothalamus, consisting mainly of nerve fibers and neuroglial cells.
Discuss the origin of each gland: The anterior pituitary originates from an invagination of the oral ectoderm called Rathke's pouch, while the posterior pituitary is an extension of the hypothalamic neurons.
Explain the hormone production: The anterior pituitary produces and secretes its own hormones, including growth hormone (GH), prolactin (PRL), follicle-stimulating hormone (FSH), luteinizing hormone (LH), thyroid-stimulating hormone (TSH), and adrenocorticotropic hormone (ACTH). The posterior pituitary does not produce hormones but stores and secretes hormones produced by the hypothalamus, namely oxytocin and vasopressin (antidiuretic hormone, ADH).
Describe the regulation mechanism: The anterior pituitary's hormone secretion is regulated by releasing and inhibiting hormones from the hypothalamus, transported through the hypophyseal portal system. The posterior pituitary's hormone release is controlled by nerve impulses from the hypothalamus.
Summarize the functional differences: The anterior pituitary primarily regulates various physiological processes including growth, metabolism, and reproductive functions through its hormones. The posterior pituitary mainly plays a role in water balance and uterine contractions during childbirth through its stored hormones.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Pituitary Gland Structure

The pituitary gland, often referred to as the 'master gland,' is divided into two main parts: the anterior pituitary and the posterior pituitary. The anterior pituitary is composed of glandular tissue that produces and secretes hormones, while the posterior pituitary is made of neural tissue and stores hormones produced by the hypothalamus. This structural distinction is crucial for understanding their different functions.
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Hormonal Functions

The anterior pituitary produces several key hormones, including growth hormone, prolactin, and adrenocorticotropic hormone, which regulate various bodily functions such as growth, metabolism, and stress response. In contrast, the posterior pituitary primarily releases oxytocin and vasopressin (antidiuretic hormone), which are involved in childbirth, lactation, and water balance. Understanding these hormonal functions is essential for comparing the roles of the two gland regions.
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Regulatory Mechanisms

The anterior pituitary is regulated by releasing and inhibiting hormones from the hypothalamus, which control its hormone secretion. The posterior pituitary, however, does not produce hormones but releases them into the bloodstream in response to neural signals from the hypothalamus. This difference in regulatory mechanisms highlights the distinct ways in which the two parts of the pituitary gland operate within the endocrine system.
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