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Ch. 21 - Genomes and Their Evolution

Chapter 21, Problem 4

DRAW IT Below are the amino acid sequences (using single letters; see Figure 5.14) of three short segments of the FOXP2 protein from five species. These segments contain all amino acid differences between the FOXP2 proteins of these species. Compare the amino acid sequences by answering parts (a)–(d). Chimpanzee PKSSD ... TSSTT ... NARRD Mouse PKSSE ... TSSTT ... NARRD Gorilla PKSSD ... TSSTT ... NARRD Human PKSSD ... TSSNT ... SARRD Rhesus monkey PKSSD ... TSSTT ... NARRD (a)Circle the names of any species that have identical amino acid sequences for the FOXP2 protein.

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Welcome back. Here's our next question based on three short segments of fox P, two proteins of four animal species. How many amino acids in the human sequence are different from those in the Z. Finch sequence. So, first of all, we'll look for our human and Z. Finch in the list of the species there. So we're going to find out, look compare the two amino acid sequences and count how many amino acids are different between them, so they're handily right next to each other. So let's compare the first segment. We see one different here and the second segment we see one right there, that's different. And in the third segment this last amino acid. So as we can see there's three amino acids in which these two sequences differ from each other. So go down to our answer choices and we see that choice C is 3. 3 amino acids, differentiate these two amino acid sequences. So that was a nice, really straightforward problem for us. And we'll see you in the next video.
Related Practice
Textbook Question

(c)In the human sequence, underline any amino acid that differs from the sequence for the chimpanzee, gorilla, and rhesus monkey.

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Textbook Question

Homeotic genes a. encode transcription factors that control the expression of genes responsible for specific anatomical structures. b. are found only in Drosophila and other arthropods. c. are the only genes that contain the homeobox domain. d. encode proteins that form anatomical structures in the fly.

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Textbook Question

Two eukaryotic proteins have one domain in common but are otherwise very different. Which of the following processes is most likely to have contributed to this similarity? a. gene duplication b. alternative splicing c. exon shuffling d. random point mutations

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Textbook Question

(b)In the sequence for the mouse, circle any amino acid that differs from the sequence for the chimpanzee, gorilla, and rhesus monkey. Then draw a box around any amino acid that differs from the human sequence.

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Textbook Question

Below are the amino acid sequences (using single letters; see Figure 5.14) of three short segments of the FOXP2 protein from five species. These segments contain all amino acid differences between the FOXP2 proteins of these species. Compare the amino acid sequences by answering parts (a)–(d).


b. In the sequence for the mouse, circle any amino acid that differs from the sequence for the chimpanzee, gorilla, and rhesus monkey. Then draw a box around any amino acid that differs from the human sequence.

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Textbook Question

(d)Primates and rodents diverged about 65 million years ago, and chimpanzees and humans diverged about 6 million years ago (see Figure 21.17). How many amino acid differences are there between the sequence for the mouse and the sequence for the chimpanzee, gorilla, and rhesus monkey? How many amino acid differences are there between the human se-quence and the sequence for the chimpanzee, gorilla, and rhesus monkey? Based solely on the numbers of amino acid differences occurring over these time periods, what might you hypothesize about the rate of evolution of the FOXP2gene? Based on the information in the chapter regarding the FOXP2 gene, is your hypothesis correct?

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