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Ch. 21 - Genomes and Their Evolution

Chapter 21, Problem 4c

Below are the amino acid sequences (using single letters; see Figure 5.14) of three short segments of the FOXP2 protein from five species. These segments contain all amino acid differences between the FOXP2 proteins of these species. Compare the amino acid sequences by answering parts (a)–(d).


b. In the sequence for the mouse, circle any amino acid that differs from the sequence for the chimpanzee, gorilla, and rhesus monkey. Then draw a box around any amino acid that differs from the human sequence.

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Hi everyone Next, we'll look at the question based on the sequence alignment of the different species, in how many amino acids from sequences 10 to to frog and fish differ. So we have our different amino acid sequences here. I'm first going to find frog and fish there down at the bottom here And then I want to remember that. It's asking me only to look at sequences 10-15. So I'm going to highlight that here so that I don't um accidentally look at the whole sequence or too far here and then it says, and how many of these amino acids are they different? So we'll look at this segment here and highlight in red, the areas where the amino acids are different. So the first two columns are the same. The third is different and then the fifth over here has different amino acids. So in just that segment of 10 and 15 we see that there are just two different amino acids. So our answer choices. C. Two. So that was a pretty straightforward question. And we'll see you in the next video
Related Practice
Textbook Question

Two eukaryotic proteins have one domain in common but are otherwise very different. Which of the following processes is most likely to have contributed to this similarity? a. gene duplication b. alternative splicing c. exon shuffling d. random point mutations

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Textbook Question
DRAW IT Below are the amino acid sequences (using single letters; see Figure 5.14) of three short segments of the FOXP2 protein from five species. These segments contain all amino acid differences between the FOXP2 proteins of these species. Compare the amino acid sequences by answering parts (a)–(d). Chimpanzee PKSSD ... TSSTT ... NARRD Mouse PKSSE ... TSSTT ... NARRD Gorilla PKSSD ... TSSTT ... NARRD Human PKSSD ... TSSNT ... SARRD Rhesus monkey PKSSD ... TSSTT ... NARRD (a)Circle the names of any species that have identical amino acid sequences for the FOXP2 protein.
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Textbook Question

(b)In the sequence for the mouse, circle any amino acid that differs from the sequence for the chimpanzee, gorilla, and rhesus monkey. Then draw a box around any amino acid that differs from the human sequence.

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Textbook Question

(d)Primates and rodents diverged about 65 million years ago, and chimpanzees and humans diverged about 6 million years ago (see Figure 21.17). How many amino acid differences are there between the sequence for the mouse and the sequence for the chimpanzee, gorilla, and rhesus monkey? How many amino acid differences are there between the human se-quence and the sequence for the chimpanzee, gorilla, and rhesus monkey? Based solely on the numbers of amino acid differences occurring over these time periods, what might you hypothesize about the rate of evolution of the FOXP2gene? Based on the information in the chapter regarding the FOXP2 gene, is your hypothesis correct?

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