Fill in the blanks: Tight junctions make the spaces between cells____, whereas desmosomes increase the____of a tissue.

Video transcript

Hey, everyone. Let's take a look at this question together. If tight junctions limit the passage of molecules and ions through the space between cells, what mediates direct cell to cell contacts and provides Anchorage sites for intermediate filaments that are important for the maintenance of tissue architecture. Is it answer choice. A desmosome answer choice B collagen, answer choice C elastin or answer choice D spectrin. Let's work this problem out together to try to figure out which of the following answer choices, mediates direct cell to cell contacts, providing Anchorage sites for intermediate filaments that are important for the maintenance of tissue architecture. So in order to solve this question, we have to recall which of the following answers. Choices is related to direct cell to cell contacts and providing Anchorage sites for intermediate filaments, which we can identify when we are talking about those Anchorage sites. We are talking about the bottom of the cells. And in this case, we can identify that answer choice. A desmosome represent major intracellular adhesive junctions that are found at the basolateral membranes of the epithelial cells, which is at the bottom where that Anchorage site is found in the epithelial cells as well as other tissues and the desmosome mediate that direct cell to cell contact and provide the Anchorage sites for the intermediate filaments that are important for the maintenance of tissue architecture. So answer choice. A desmosome is the correct answer. And we also know that answer choice BC and D are all incorrect. Since answer choices, BC and D are all types of cell proteins and not related to junctions between cells. So answer choice. A desmosome is the correct answer. I hope you found this video to be helpful. Thank you and goodbye.