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Ch. 25 Fluid, Electrolyte, and Acid-Base Homeostasis
Chapter 25, Problem 25.3a

Explain how the amount of water in the body affects the concentration of ions and solutes in the ECF.

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Step 1: Understand that the body's water content and the concentration of ions and solutes in the extracellular fluid (ECF) are closely linked. The ECF is the body fluid that is outside of the cells, and it includes interstitial fluid, blood plasma, and other bodily fluids.
Step 2: Recognize that when the body's water content is high, the concentration of ions and solutes in the ECF is diluted. This is because the additional water decreases the relative amount of ions and solutes, leading to a lower concentration.
Step 3: Conversely, when the body's water content is low, the concentration of ions and solutes in the ECF is increased. This is because there is less water to 'dilute' the ions and solutes, leading to a higher concentration.
Step 4: Understand that the body maintains a balance of water and solutes through mechanisms such as thirst and the release of antidiuretic hormone (ADH). When the concentration of solutes in the ECF is high (indicating dehydration), the body triggers thirst and releases ADH to promote water retention and intake, which will dilute the ECF and lower the solute concentration.
Step 5: Remember that maintaining the right balance of water and solutes in the body is crucial for physiological processes such as nerve impulse transmission, muscle contraction, and maintaining blood pressure.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Extracellular Fluid (ECF)

Extracellular fluid refers to all body fluids outside of cells, including interstitial fluid and plasma. It plays a crucial role in maintaining homeostasis by providing a medium for nutrient and waste exchange. The concentration of ions and solutes in the ECF is vital for cellular function, as it influences osmotic balance and electrical gradients across cell membranes.
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Osmolarity

Osmolarity is a measure of the concentration of solutes in a solution, expressed as osmoles of solute per liter of solution. In the context of ECF, changes in water volume directly affect osmolarity; an increase in water dilutes solutes, while a decrease concentrates them. This balance is essential for proper physiological functions, including nerve impulse transmission and muscle contraction.

Homeostasis

Homeostasis is the process by which biological systems maintain stability while adjusting to changing external conditions. The body regulates the concentration of ions and solutes in the ECF to ensure optimal functioning of cells and organs. Disruptions in water balance can lead to conditions such as dehydration or overhydration, which can significantly impact homeostatic mechanisms.
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Related Practice
Textbook Question

A woman begins a diet and exercise regimen and loses 30 lb. Will her total body water increase, decrease, or stay the same? Why?

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Textbook Question

What do you think has happened to Elise's ECF volume and osmolarity over the past 3 days? Will this lead to a change in the volume of water in the cytosol of her cells? Explain.

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Textbook Question

What happens to the pH of a solution when hydrogen ions are added?


a. The pH increases.

b. The pH decreases.

c. The pH does not change.

d. The pH does not measure hydrogen ion concentration.

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Textbook Question

Ms. Johanssen is a patient in the hospital. The nurse examines her laboratory reports and notices that she has developed hyperkalemia and acidosis over the past several days. On closer examination of her medical chart, the nurse also sees that her physician recently doubled her dose of spironolactone, an aldosterone-blocking diuretic. How does this explain her laboratory findings?

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Textbook Question

As a percentage of body weight, the total body water tends to be higher in ________ and lower in ________ ​.


a. ​infants; men

b. women; men

c. men; infants

d. infants; women

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Textbook Question

Diabetic ketoacidosis is characterized by an increased level of ketone bodies, which causes metabolic acidosis. A patient in diabetic ketoacidosis will have an altered rate of ventilation. Will the patient be hyperventilating or hypoventilating? How will a change in the rate and depth of ventilation compensate for an acidosis that is metabolic in nature?

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