The anticoagulant drug warfarin primarily disrupts the extrinsic/tissue factor coagulation pathway. Explain why disrupting only this pathway disrupts the entire coagulation cascade.

Video transcript

Hey, everyone. Let's take a look at this question together identify the coagulation pathway that is primarily disrupted by the anticoagulant drug warfarin. Is it answer choice. A the intrinsic or contact activation pathway? Answer choice B, the extrinsic or tissue factor pathway. Answer choice C the common pathway or answer choice D all of the above. Let's work this problem out together to try to figure out which of the following answer choices contains the coagulation pathway that is primarily disrupted by warfarin. So in order to solve this question, we have to recall what we have learned about the different coagulation pathways and the effects of the anticoagulant drug warfarin to determine which of the following pathways is primarily disrupted. And we can recall that Warfarin inhibits the production of those vitamin K dependent clotting factors, which the vitamin K dependent clotting factors whose production is inhibited by Warfarin includes factors too 79 and factor 10. And as a result of the production of those factors being inhibited. Warfarin disrupts the extrinsic or tissue factor pathway, which means that answer choice B, extrinsic tissue factor pathway is the correct answer. As that is the coagulation pathway that is primarily disrupted by the anticoagulant drug warfarin and all other answer choices are incorrect. I hope you found this video to be helpful. Thank you and goodbye.