Chapter 19, Problem 19.4a
Elise is a 36-year-old woman who has volunteered to donate red bone marrow to a patient in need of a bone marrow transplant for aplastic anemia. The physician performing the bone marrow extraction is an intern, and it is her first time doing the procedure. She asks that you prepare a site on Elise's tibia for the procedure. Is this a good place for red bone marrow to be extracted, considering Elise's age? Why or why not? Can you suggest an alternative location? Explain.
Video transcript
The anticoagulant drug warfarin primarily disrupts the extrinsic/tissue factor coagulation pathway. Explain why disrupting only this pathway disrupts the entire coagulation cascade.
Ms. Wu, whose blood type is O−, requires a blood transfusion. Her family members volunteer to donate blood. Their blood types are as follows: her son, type B−; her husband, type B+; her daughter, type O+. Which family members could safely donate blood to Ms. Wu? Who could not? Explain.
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
a. Erythrocytes are biconcave discs with prominent nuclei.
Cirrhosis of the liver often reduces production of many types of plasma proteins, including albumin and clotting factors. Predict the effects on the body of decreased numbers of these proteins in the plasma. Would this also affect the number of γ-globulins in the plasma? Why or why not?
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
b. The main function of erythrocytes is to transport oxygen on the protein hemoglobin.
Mark the following statements as true or false. If a statement is false, correct it to make a true statement.
c. Hemoglobin forms oxyhemoglobin when it binds to oxygen.