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Ch. 10 Muscle Tissue and Physiology

Chapter 10, Problem 10.5a

What is the basic mechanism of contraction at the level of myofilaments?

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Hey, everyone. Let's take a look at this question together which of the following happens during the resting state of the muscle contraction cycle. Is it answer choice. A calcium ions bind to troponin. Answer choice. Batp is hydrolyzed to ad P answer choice C Tropomyosin blocks the active sites on acting or answer choice. Datp molecules binds to the Myosin head. Let's work this problem out together to try to figure out which of the following answer choices best explains what happens during the resting state of the muscle contraction cycle. So in order to solve this question, we have to recall what we have learned about the muscle contraction cycle and what occurs during the resting state. And we can recall that in the resting state of muscle contraction, the formation of the Myosin cross bridges are blocked. And what we mean by the Myosin cross bridge formation is blocked is that Tropomyosin covers the act in binding site which prevents the formation of the cross bridge. So during the resting state of the muscle contraction cycle, the formation of the cross bridges is blocked because Tropomyosin binds to the active sites on active, which is answer choice C the correct answer and all other answer choices are incorrect. Since answer choice A which says calcium ions bind to troponin is incorrect. Since the bind of calcium ions to troponin occurs in the activation phase. Answer choice B which says A TP is hydrolyzed to AD P is incorrect. Since the hydro organization of A TP into AD P is part of the energy dependent steps during the contraction cycle but occurs after the resting state when the muscle is activated. And lastly answer choice D which says A TP molecules bind to the myosin head is incorrect. Since the binding of the A TP molecules to the myosin head occurs during the later stages of the contraction cycle. When the myosin head is preparing for the formation of another cross bridge. And answer choice C is the only correct answer choice. I hope you found this video to be helpful. Thank you and goodbye.
Related Practice
Textbook Question

Ms. Sanchez was in a motorcycle accident in which she lost the use of her right upper limb muscles due to significant nerve damage. However, when an electrode is inserted into her muscles, they are able to contract. Explain specifically why nerve damage caused her to lose the use of her muscles. Why can they still respond to stimulation from an electrode?

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Textbook Question

Match the following terms with the correct definition.      


____Z-disc     

____Sarcomere     

____A band     

____H zone     

____I band     

____M line


a. The dark band containing the entire length of the thick filament

b. The band of proteins in the middle of the H zone

c. The boundary between sarcomeres

d. The functional unit of contraction

e. The middle region of the A band containing only thick filaments

f. The light band containing only thin filaments

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Textbook Question

Mr. Nasheed has cerebral palsy and suffers severe skeletal muscle spasms as a result of his condition. He is prescribed the drug dantrolene, which prevents the release of Ca2+ from the SR. Explain how this will treat his muscle spasms.

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Textbook Question

Jesse is a 2-year-old boy who presents with difficulty in walking and poor control of movements. When the doctor examines Jesse, she notices that when his muscles contract, they are very slow to relax and remain contracted well after the movement has been performed. She sends a sample of his tissue for genetic analysis, and the lab reports a genetic defect that causes the pumps in the SR to operate much more slowly than normal. How does a defect in DNA lead to a malfunctioning protein? How does this finding explain Jesse's symptoms? (Connects to Chapter 3)

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Textbook Question

Paola is a 3-year-old girl with a disease that reduces the ability of her mitochondria to generate ATP. Explain the specific effects of this disease on the ability of Paola's muscles to function properly. What other tissues and organs are likely to be especially affected by her disease, and why? (Connects to ​Chapter 3​)

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Textbook Question

Order the following events of excitation and excitation-contraction coupling. Put 1 by the first event, 2 by the second, and so on.


          ​​​​

____The motor end plate generates an end-plate potential.          ​​​​

____The action potential spreads along the T-tubules, SR Ca2+ channels are pulled open, and Ca2+ flood the cytosol.          ​​​​

____Acetylcholine binds to receptors on the motor end plate, and ligand-gated ion channels open.          ​​​​

____Ca2+ bind troponin, which allows tropomyosin to move away from the actin active site, initiating a contraction cycle.          ​​​​

____The action potential propagates through the sarcolemma and dives deeply into the cell along the T-tubules.

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