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Ch. 13 - Viruses, Viroids, and Prions
Chapter 10, Problem 13.1a

Why do we classify viruses as obligatory intracellular parasites?

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Viruses lack the cellular machinery necessary for their own replication, such as ribosomes and enzymes needed for protein synthesis.
They must enter a host cell to utilize the host's machinery to replicate and produce new virus particles.
Once inside the host cell, viruses hijack the host's cellular processes to synthesize viral components.
The host cell provides the necessary environment and resources, such as nucleotides and amino acids, for viral replication.
This dependency on a host cell for replication is why viruses are classified as obligatory intracellular parasites.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Obligatory Intracellular Parasites

Obligatory intracellular parasites are organisms that can only reproduce and carry out their life cycle within the cells of a host. Viruses fall into this category because they lack the cellular machinery necessary for metabolism and replication, relying entirely on the host's cellular processes to produce new viral particles.
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General Structure of Viruses

Viral Structure and Function

Viruses are composed of genetic material (either DNA or RNA) encased in a protein coat, and sometimes a lipid envelope. This simple structure allows them to efficiently invade host cells, where they hijack the host's machinery to replicate their genetic material and produce viral proteins, ultimately leading to the assembly of new virions.
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Functional Groups

Host-Pathogen Interaction

The interaction between a virus and its host is critical for understanding viral infections. Viruses attach to specific receptors on host cells, facilitating entry and subsequent replication. This relationship highlights the parasitic nature of viruses, as they exploit host resources for their own reproduction, often causing damage or disease in the process.
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