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Ch.17 Carboxylic Acids and Their Derivatives
Chapter 17, Problem 20b

Draw structures of the amides that can be made from the following reactants:


b. <IMAGE>

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1
Identify the reactants involved in the formation of an amide. Typically, an amide is formed from a carboxylic acid and an amine.
Determine the functional groups present in the reactants. Look for the carboxyl group (-COOH) in the carboxylic acid and the amino group (-NH2) in the amine.
Consider the reaction mechanism: the carboxylic acid reacts with the amine to form an amide bond (-CONH-), releasing a molecule of water (H2O) in a condensation reaction.
Draw the structure of the amide by connecting the carbonyl carbon of the carboxylic acid to the nitrogen of the amine, ensuring the removal of the hydroxyl group from the acid and a hydrogen from the amine to form water.
Verify the structure by checking that the amide bond is correctly formed and that the remaining parts of the original reactants are intact, ensuring the correct connectivity and geometry.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Amides

Amides are organic compounds derived from carboxylic acids where the hydroxyl group (-OH) is replaced by an amine group (-NH2, -NHR, or -NR2). They are characterized by the functional group -C(=O)N-, which is crucial for their chemical properties and reactivity. Understanding the structure of amides is essential for predicting their behavior in chemical reactions.
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Reactants

Reactants are the starting materials in a chemical reaction that undergo transformation to form products. In the context of amide formation, common reactants include carboxylic acids and amines. Identifying the correct reactants is vital for drawing the resulting amide structures accurately.
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Chemical Structure Drawing

Chemical structure drawing involves representing the arrangement of atoms within a molecule using symbols and lines. This skill is essential for visualizing molecular geometry and understanding functional groups. Accurately drawing the structures of amides formed from specific reactants helps in comprehending their properties and potential reactions.
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