What is the role of the enzyme aromatase in sexual differentiation in reptiles?

Video transcript

Welcome back. Let's look at the next problem. It says the aroma taste enzyme is responsible for a crucial stage in the manufacturer of and we have four different sort of sex specific hormones here. A testosterone be estrogen c oxytocin D progesterone testosterone of course, being that determiner of sex characteristics in males and the development of their um sexual organs. Um estrogen serving that purpose for females and then oxytocin and progesterone along with estrogen um playing roles in the regulation of the female menstrual cycle. Um The aroma taste enzyme is responsible for a crucial stage in the manufacture of choice. Be estrogen it catalyze is that last step in the manufacture of estrogen which is actually manufactured from androgens from those male um hormone male steroids, male hormones. Uh It capitalizes the aroma tis ation of androgens. That's why it gets where it gets its name aroma taste. Uh It converts one of the rings in androgen molecules to an aromatic state, which is that more stable state with multiple double bonds. And it is. This step is carried out in the placenta during pregnancy which prevents androgens from directing the sexual development of the fetus. So that's the role of Roma, tastes very crucial in that manufacturer interestingly. It's also um remote ace inhibitors are candidates for cancer drugs uh particularly in breast cancer for breast cancer that's sensitive to estrogen because an aroma taste inhibitor can lower estrogen levels helping to treat those kinds of breast cancers. So again the aromatase enzyme responsible for a crucial stage in the manufacture of choice. Be estrogen. See you in the next video.