Ch. 5 - Chromosome Mapping in Eukaryotes
Chapter 5, Problem 14
In Drosophila, a cross was made between females—all expressing the three X-linked recessive traits scute bristles (sc), sable body (s), and vermilion eyes (v)—and wild-type males. In the F₁, all females were wild type, while all males expressed all three mutant traits. The cross was carried to the F₂ generation, and 1000 offspring were counted, with the results shown in the following table. Phenotype Offspring sc s v 314 + + + 280 + s v 150 sc + + 156 sc + v 46 + s + 30 sc s + 10 + + v 14 No determination of sex was made in the data. Are there more or fewer double crossovers than expected?
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Textbook Question
As in Problem 12, flower color may be red, white, or pink, and flower shape may be personate or peloric. For the following crosses, determine the P₁ and F₁ genotypes:
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Textbook Question
In Drosophila, a cross was made between females—all expressing the three X-linked recessive traits scute bristles (sc), sable body (s), and vermilion eyes (v)—and wild-type males. In the F₁, all females were wild type, while all males expressed all three mutant traits. The cross was carried to the F₂ generation, and 1000 offspring were counted, with the results shown in the following table.
Phenotype Offspring
sc s v 314
+ + + 280
+ s v 150
sc + + 156
sc + v 46
+ s + 30
sc s + 10
+ + v 14
No determination of sex was made in the data.
Using proper nomenclature, determine the genotypes of the P₁ and F₁ parents.
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Textbook Question
In Drosophila, a cross was made between females—all expressing the three X-linked recessive traits scute bristles (sc), sable body (s), and vermilion eyes (v)—and wild-type males. In the F₁, all females were wild type, while all males expressed all three mutant traits. The cross was carried to the F₂ generation, and 1000 offspring were counted, with the results shown in the following table.
Phenotype Offspring
sc s v 314
+ + + 280
+ s v 150
sc + + 156
sc + v 46
+ s + 30
sc s + 10
+ + v 14
No determination of sex was made in the data.
Determine the sequence of the three genes and the map distances between them.
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Textbook Question
In Drosophila, a cross was made between females—all expressing the three X-linked recessive traits scute bristles (sc), sable body (s), and vermilion eyes (v)—and wild-type males. In the F₁, all females were wild type, while all males expressed all three mutant traits. The cross was carried to the F₂ generation, and 1000 offspring were counted, with the results shown in the following table.
Phenotype Offspring
sc s v 314
+ + + 280
+ s v 150
sc + + 156
sc + v 46
+ s + 30
sc s + 10
+ + v 14
No determination of sex was made in the data.
Calculate the coefficient of coincidence. Does it represent positive or negative interference?
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Textbook Question
Another cross in Drosophila involved the recessive, X-linked genes yellow (y), white (w), and cut (ct). A yellow-bodied, white-eyed female with normal wings was crossed to a male whose eyes and body were normal but whose wings were cut. The F₁ females were wild type for all three traits, while the F₁ males expressed the yellow-body and white-eye traits. The cross was carried to an F₂ progeny, and only male offspring were tallied. On the basis of the data shown here, a genetic map was constructed.
Phenotype Male Offspring
y + ct 9
+ w + 6
y w ct 90
+ + + 95
+ + ct 424
y w + 376
y + + 0
+ w ct 0
Diagram the genotypes of the F₁ parents.
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Textbook Question
Another cross in Drosophila involved the recessive, X-linked genes yellow (y), white (w), and cut (ct). A yellow-bodied, white-eyed female with normal wings was crossed to a male whose eyes and body were normal but whose wings were cut. The F₁ females were wild type for all three traits, while the F₁ males expressed the yellow-body and white-eye traits. The cross was carried to an F₂ progeny, and only male offspring were tallied. On the basis of the data shown here, a genetic map was constructed.
Phenotype Male Offspring
y + ct 9
+ w + 6
y w ct 90
+ + + 95
+ + ct 424
y w + 376
y + + 0
+ w ct 0
Construct a map, assuming that white is at locus 1.5 on the X chromosome.
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