Ch. 5 - Chromosome Mapping in Eukaryotes
Chapter 5, Problem 19
If the cross described in Problem 18 were made, and if Sb and cu are 8.2 map units apart on chromosome III, and if 1000 offspring were recovered, what would be the outcome of the cross, assuming that equal numbers of males and females were observed?
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Textbook Question
In Drosophila, Dichaete (D) is a mutation on chromosome III with a dominant effect on wing shape. It is lethal when homozygous. The genes ebony body (e) and pink eye (p) are recessive mutations on chromosome III. Flies from a Dichaete stock were crossed to homozygous ebony, pink flies, and the F₁ progeny, with a Dichaete phenotype, were backcrossed to the ebony, pink homozygotes. Using the results of this backcross shown in the table,
Phenotype Number
Dichaete 401
ebony, pink 389
Dichaete, ebony 84
pink 96
Dichaete, pink 2
ebony 3
Dichaete, ebony, pink 12
wild type 13
Diagram this cross, showing the genotypes of the parents and offspring of both crosses.
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Textbook Question
Drosophila females homozygous for the third chromosomal genes pink and ebony (the same genes from Problem 16) were crossed with males homozygous for the second chromosomal gene dumpy. Because these genes are recessive, all offspring were wild type (normal). F₁ females were testcrossed to triply recessive males. If we assume that the two linked genes, pink and ebony, are 20 mu apart, predict the results of this cross. If the reciprocal cross were made (F₁ males—where no crossing over occurs—with triply recessive females), how would the results vary, if at all?
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Textbook Question
In Drosophila, two mutations, Stubble (Sb) and curled (cu), are linked on chromosome III. Stubble is a dominant gene that is lethal in a homozygous state, and curled is a recessive gene. If a female of the genotype
is to be mated to detect recombinants among her offspring, what male genotype would you choose as a mate?
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Textbook Question
Are mitotic recombinations and sister chromatid exchanges effective in producing genetic variability in an individual? in the offspring of individuals?
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Textbook Question
What possible conclusions can be drawn from the observations that in male Drosophila, no crossing over occurs, and that during meiosis, synaptonemal complexes are not seen in males but are observed in females where crossing over occurs?
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Textbook Question
An organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are presented in the following table.
20 AaBbCc 20 AaBbcc
20 aabbCc 20 aabbcc
5 AabbCc 5 Aabbcc
5 aaBbCc 5 aaBbcc
If these three genes were all assorting independently, how many genotypic and phenotypic classes would result in the offspring, and in what proportion, assuming simple dominance and recessiveness in each gene pair?
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