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Ch. 25 - Quantitative Genetics and Multifactorial Traits
Chapter 24, Problem 10

List as many human traits as you can that are likely to be under the control of a polygenic mode of inheritance.

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Understand that polygenic inheritance involves multiple genes contributing to a single trait, often resulting in a continuous distribution of phenotypes.
Recognize that traits controlled by polygenic inheritance often show a range of variations, such as height, skin color, and eye color.
Consider traits that do not follow simple Mendelian inheritance patterns, as these are likely candidates for polygenic inheritance.
Identify common human traits that exhibit a wide range of phenotypes, suggesting the influence of multiple genes.
List traits such as height, skin color, eye color, weight, intelligence, and susceptibility to certain diseases as examples of polygenic traits.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Polygenic Inheritance

Polygenic inheritance refers to the genetic mechanism where multiple genes (often located on different chromosomes) contribute to a single trait. This results in a continuous range of phenotypes, as opposed to discrete categories. Examples include traits like height, skin color, and eye color, which are influenced by the additive effects of several alleles.
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Quantitative Traits

Quantitative traits are characteristics that show a continuous distribution in a population, such as height or weight. These traits are typically influenced by multiple genes and environmental factors, making them complex to study. The phenotypic variation in quantitative traits can often be measured and analyzed statistically.
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Environmental Influence on Traits

The expression of polygenic traits can be significantly affected by environmental factors, such as nutrition, climate, and lifestyle. This interaction between genes and the environment can lead to variations in the phenotype that are not solely determined by genetic makeup. Understanding this concept is crucial for comprehending how traits manifest in real-world scenarios.
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Related Practice
Textbook Question

Erma and Harvey were a compatible barnyard pair, but a curious sight. Harvey's tail was only 6 cm long, while Erma's was 30 cm. Their F₁ piglet offspring all grew tails that were 18 cm. When inbred, an F₂ generation resulted in many piglets (Erma and Harvey's grandpigs), whose tails ranged in 4-cm intervals from 6 to 30 cm (6, 10, 14, 18, 22, 26, and 30). Most had 18-cm tails, while 1/64 had 6-cm tails and 1/64 had 30-cm tails. If one of the 18-cm-tail F₁ pigs is mated with one of the 6-cm-tail F₂ pigs, what phenotypic ratio will be predicted if many offspring resulted? Diagram the cross.

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Textbook Question

In the following table, average differences of height, weight, and fingerprint ridge count between monozygotic twins (reared together and apart), dizygotic twins, and nontwin siblings are compared:   Trait            MZ Reared    MZ        DZ Reared   Sibs Reared                     Together      Reared     Together       Together                                          Apart                                              _Height (cm)      1.7              1.8             4.4                4.5 Weight (kg)      1.9               4.5            4.5                4.7 Ridge count     0.7               0.6            2.4                 2.7 Based on the data in this table, which of these quantitative traits has the highest heritability values?

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Textbook Question

What kind of heritability estimates (broad sense or narrow sense) are obtained from human twin studies?

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Textbook Question

Corn plants from a test plot are measured, and the distribution of heights at 10-cm intervals is recorded in the following table:  

 Height (cm)      Plants (no.)       

100                    20       

110                    60       

120                    90       

130                   130       

140                   180      

 150                   120       

160                    70        

170                   50        

180                   40 

Calculate 

(a) the mean height, 

(b) the variance, 

(c) the standard deviation, and 

(d) the standard error of the mean. 

Plot a rough graph of plant height against frequency. Do the values represent a normal distribution? Based on your calculations, how would you assess the variation within this population?

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Textbook Question

The following variances were calculated for two traits in a herd of hogs.

  Trait             Vₚ           VG        VA  _
Back fat        30.6        12.2       8.44
Body length  52.4        26.4     11.70

Which of the two traits will respond best to selection by a breeder? Why?

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Textbook Question

The following variances were calculated for two traits in a herd of hogs.

  Trait             Vₚ           VG        VA  _
Back fat        30.6        12.2       8.44
Body length  52.4        26.4     11.70

Calculate broad-sense (H²) and narrow-sense (h²) heritabilities for each trait in this herd.

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