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Ch. 24 - Cancer Genetics

Chapter 23, Problem 11

Part of the Ras protein is associated with the plasma membrane, and part extends into the cytoplasm. How does the Ras protein transmit a signal from outside the cell into the cytoplasm? What happens in cases where the ras gene is mutated?

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Hi everyone, welcome back. Here's our next problem Blank are the most frequently found. Anka genes in humans, mutations in these genes are detected in 20-25% of all human human malignancies and up to 90% of some forms of cancer. So we're looking for the most frequently found ankle genes in human ankle jeans. Being genes involved in cancer causing cancer increased susceptibility to cancer. So let's work through our answer choices here, noticing that choice D. Is all of the above. So there's a chance that all of these answers are correct. Choice A. Is raz jeans. And those raz jeans are code for proteins that are involved in helping to control cell growth and death. So let's put that in here. Well, as you would suspect, proteins that help control cell growth and programmed cell death or apoptosis are definitely ankle jeans because if something goes wrong with them, you have uncontrolled cell growth, that failure of necessary apoptosis. So raz genes are the most frequently found. Uncle genes in humans. Um we can highlight that and we wouldn't have expected to have choice D. All of the above because our answer choice says the most frequently found. So you wouldn't expect even if the others are uncle genes as we go through, we're looking for the most frequent ones which we can recall our the razz genes. So we're going to go ahead and eliminate choice D. All the above. But we'll look at those other answer choices to be thorough choice B is cap jeans. Cap is the metabolite activator protein and it is an activator for the lack opera on when the molecule C. A. M. P. Binds to it. In the absence of glucose, it activates the lack operation. It helps RNA preliminaries to bind tightly to its binding site, turning up production of the lack genes but not our answer. They're not uncle jeans so we're going to cross that out. And then finally, Choice C. A. T. M. A. T. M proteins help coordinate DNA repair and they activate enzymes that uh fix broken strands of D. N. A. But they all that's important. They are not ankle jeans that we can cross that out. So again, the choice A wrasse genes are the most frequently found. Uncle genes in humans. See you in the next video.