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Ch. 24 - Cancer Genetics
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All textbooksKlug 12th EditionCh. 24 - Cancer GeneticsProblem 19

Chapter 23, Problem 19

Describe the difference between an acute transforming virus and a virus that does not cause tumors.

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Hi everyone, welcome back. Let's look at our next problem. It says hepatitis B virus is associated with. And we've got four different types of cancers here listed. A Burkitt lymphoma B. Nasopharyngeal carcinoma. I see Geppetto cellular carcinoma and d hodgkin lymphoma. And if we can't remember off the top of our heads, one thing to kind of keep in mind if we were trying to figure this out on a test, we have Hepatitis B and when we look at choice, see it's hepatitis cellular carcinoma. So hepatic cellular would involve the liver. So and of course the HEPA prefix there and hepatitis also indicates that it's something affecting the liver. So that should point you to the correct answer. Which is choice C apatow cellular carcinoma. Hepatitis B virus causes inflammation in the liver which then leads to scarring called cirrhosis and then can lead to actual cancer. So let's look at our other answer choices just to understand why they're not correct choice. A Burkitt lymphoma, a lymphoma would be cancer of the lymphatic symptom and this is associated a higher risk of Burkitt lymphoma is associated with a viral infection but its previous infection with the Epstein Barr virus which can cause mono infection. Um This there's a known association although it's a fairly low increase in risk but that is the virus that's associated with an increased risk of Burkitt lymphoma. That's why that's not correct. Since we're looking for something associated with Hepatitis B. Choice B. Nasopharynx, real carcinoma um cancer of the nose, the nose and throat region and this is a rather rare form of cancer also slightly associated with previous Epstein Barr virus infection. So not a correct answer. And finally, choice the Hodgkin lymphoma, another cancer of the lymphatic symptom also associated with previous infection with Epstein barr virus. Um This is an extremely common virus, though the majority of people have been infected with it, so uh not initially something to panic about. It's just in research has been known, a slight increase in risk of these cancers known to be associated with previous infection by the Epstein Barr virus. But again, choice D not a correct answer. Hepatitis B virus is associated with YC hepatitis cellular carcinoma. See you in the next video.
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