Transcription factors play key roles in the regulation of gene expression, but to do so, they must act within the nucleus. Like most proteins, however, transcription factors are translated in the cytoplasm. To enter the nucleus, transcription factors contain nuclear localization signals, which in some cases can work only when bound to some other molecule such as a steroid hormone. After entering the nucleus, transcription factors must bind to appropriate DNA sites and must interact with other transcription proteins at promoters, enhancers, and silencers. Transcription factors then activate or repress transcription through their activation or repression domains. Many drug therapies target transcription factors. Based on the information provided above, suggest three specific mechanisms through which a successful drug therapy, targeted to a transcription factor, might work.

Video transcript

Hello everyone and welcome to today's video. Today we have that transcription factors or proteins that regulate the transcription process. So how do transcription factors differ from other gene regulators such as coated and kis? Well, let's go over each of our answer choices so that we may solve this problem. Let's begin by answer choice. A we have transcription factors are generated in trace amounts or in very low amounts. This is going to be an incorrect answer choice because transcription factors are actually generated in very high amounts as they undergo the process of transcription in the cell, which is a very important process because of this, we're going to cancel this out. Then we have the transcription factors and need stimulants before they are produced. Well, this is actually going to be incorrect as well. There is no stimulus being involved in the process of making these transcription factors. Because of this. We're going to cancel this question out. Then we have c transcription factors are only found in ate. Well, no, this is incorrect as well because they are also found in ears as well as a K A and other forms of life because of this, we're going to cancel this out as well. Then we have the transcription factors contain at least one DNA binding domain. Well as the question states, these transcription factors are going to be involved in transcription. And transcription is a process of transforming DNA. To irony, these transcription factors need at least one DNA binding domain so that they can bind into this DNA and perform the transcription process because of this. This is going to be our correct answer choice and we're going to highlight it as a final answer to our question. I really hope this helped you and I hope to see you on the next one.